gnpda1.S glucosamine-6-phosphate deaminase 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gnpda1.S
Official Full Name: glucosamine-6-phosphate deaminase 1 S homeolog
Primary source: Xenbase:XB-GENE-966380
Locus tag: XELAEV_18021471mg
See related: EnsemblRapid:ENSXLAG00005012804 AllianceGenome:Xenbase:XB-GENE-966380
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: gpi; hln; gnpi; gnpda; gnpda1
Summary: Predicted to enable glucosamine-6-phosphate deaminase activity and identical protein binding activity. Predicted to act upstream of or within N-acetylneuraminate catabolic process; carbohydrate metabolic process; and glucosamine-containing compound catabolic process. Predicted to be located in cytoplasm. Orthologous to human GNPDA1 (glucosamine-6-phosphate deaminase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3S

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3S	NC_054376.1 (109643782..109659955, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3S	NC_030729.1 (107720146..107736287, complement)

Chromosome 3S - NC_054376.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables glucosamine-6-phosphate deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables identical protein binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within N-acetylglucosamine catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within N-acetylglucosamine metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within N-acetylneuraminate catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glucosamine catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: glucosamine-6-phosphate deaminase 1 S homeolog

NP_001083469.1

EC 3.5.99.6

XP_018109658.1

EC 3.5.99.6

XP_041443492.1

EC 3.5.99.6

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001090000.1 → NP_001083469.1 glucosamine-6-phosphate deaminase 1 S homeolog

See identical proteins and their annotated locations for NP_001083469.1

Status: PROVISIONAL

Source sequence(s)

BC060459

UniProtKB/TrEMBL

Q6PA45

Related

ENSXLAP00005037667.1, ENSXLAT00005038578.1

Conserved Domains (1) summary

cl00339
Location:1 → 253

SugarP_isomerase; SugarP_isomerase: Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054376.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

109643782..109659955 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018254169.2 → XP_018109658.1 glucosamine-6-phosphate deaminase 1 S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8GVA6, A0A974D905

Conserved Domains (1) summary

cl00339
Location:1 → 253

SugarP_isomerase; Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose ...
XM_041587558.1 → XP_041443492.1 glucosamine-6-phosphate deaminase 1 S homeolog isoform X1

UniProtKB/TrEMBL

A0A1L8GVA6, A0A974D905

Conserved Domains (1) summary

cl00339
Location:1 → 253

SugarP_isomerase; Sugar Phosphate Isomerase family; includes type A ribose 5-phosphate isomerase (RPI_A), glucosamine-6-phosphate (GlcN6P) deaminase, and 6-phosphogluconolactonase (6PGL). RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose ...