wdtc1.S WD and tetratricopeptide repeats 1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: wdtc1.S
Official Full Name: WD and tetratricopeptide repeats 1 S homeolog
Primary source: Xenbase:XB-GENE-17339722
Locus tag: XELAEV_18015081mg
See related: EnsemblRapid:ENSXLAG00005008709 AllianceGenome:Xenbase:XB-GENE-17339722
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary: Predicted to act upstream of or within negative regulation of fatty acid biosynthetic process. Predicted to be located in cytoplasm and nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Orthologous to human WDTC1 (WD and tetratricopeptide repeats 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 2S

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (67963545..67989951, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2S	NC_030727.1 (63589133..63615452, complement)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of fatty acid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of Cul4-RING E3 ubiquitin ligase complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC398938

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089990.1 → NP_001083459.1 uncharacterized protein LOC398938

See identical proteins and their annotated locations for NP_001083459.1

Status: PREDICTED

Source sequence(s)

BC060468

UniProtKB/TrEMBL

A0A974DHC0, Q6PA37

Related

ENSXLAP00005025334.1, ENSXLAT00005026043.1

Conserved Domains (7) summary

COG2319
Location:39 → 223

WD40; WD40 repeat [General function prediction only]

sd00006
Location:356 → 380

TPR; TPR repeat [structural motif]

pfam00515
Location:386 → 420

TPR_1; Tetratricopeptide repeat

pfam13414
Location:356 → 420

TPR_11; TPR repeat

pfam13432
Location:392 → 457

TPR_16; Tetratricopeptide repeat

sd00039
Location:51 → 87

7WD40; WD40 repeat [structural motif]

cl02567
Location:34 → 163

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

67963545..67989951 complement

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GenBank, FASTA, Sequence Viewer (Graphics)