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large2.S LARGE xylosyl- and glucuronyltransferase 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398936, updated on 18-Sep-2024

Summary

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Official Symbol
large2.S
Official Full Name
LARGE xylosyl- and glucuronyltransferase 2 S homeolog
Primary source
Xenbase:XB-GENE-5872007
Locus tag
XELAEV_18024470mg
See related
EnsemblRapid:ENSXLAG00005020296
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
large2; gyltl1b; large2-a; gyltl1b-a; gyltl1b.S
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Genomic context

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See large2.S in Genome Data Viewer
Location:
chromosome: 4S
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4S NC_054378.1 (14153298..14185671)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4S NC_030731.1 (13551951..13584491)

Chromosome 4S - NC_054378.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase 8 interacting protein 1 S homeolog Neighboring gene peroxisomal biogenesis factor 16 S homeolog Neighboring gene PHD finger protein 21A S homeolog Neighboring gene cAMP responsive element binding protein 3-like 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68636

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glucuronosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables transferase activity IEA
Inferred from Electronic Annotation
more info
  
enables xylosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables xylosyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein O-linked mannosylation ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
xylosyl- and glucuronyltransferase LARGE2s; LARGE xylosyl- and glucuronyltransferase 2-A
Names
glycosyltransferase-like 1B S homeolog
glycosyltransferase-like 1B-A
glycosyltransferase-like protein LARGE2-A
NP_001083457.1
XP_018114994.1
XP_041447182.1
XP_041447183.1
XP_041447184.1
XP_041447185.1
XP_041447186.1
XP_041447187.1
XP_041447188.1
XP_041447189.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089988.1 → NP_001083457.1  xylosyl- and glucuronyltransferase LARGE2s

    See identical proteins and their annotated locations for NP_001083457.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060410
    UniProtKB/Swiss-Prot
    Q6PA90
    UniProtKB/TrEMBL
    A0A974D268
    Related
    ENSXLAP00005059420.1, ENSXLAT00005060869.1
    Conserved Domains (3) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:440 → 709
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
    cl21462
    Location:44 → 75
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054378.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    14153298..14185671
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041591252.1 → XP_041447186.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  2. XM_041591248.1 → XP_041447182.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  3. XM_041591249.1 → XP_041447183.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  4. XM_041591250.1 → XP_041447184.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  5. XM_041591254.1 → XP_041447188.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  6. XM_018259505.2 → XP_018114994.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  7. XM_041591253.1 → XP_041447187.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  8. XM_041591255.1 → XP_041447189.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X2

    UniProtKB/TrEMBL
    A0A1L8GDQ0, A0A974D268, A0A974HKZ3
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:440 → 709
    Glyco_transf_49; Glycosyl-transferase for dystroglycan

  9. XM_041591251.1 → XP_041447185.1  LARGE xylosyl- and glucuronyltransferase 2-A isoform X1

    UniProtKB/TrEMBL
    A0A8J0V4U5, A0A974D268
    Conserved Domains (2) summary
    cd06431
    Location:107 → 386
    GT8_LARGE_C; LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis
    pfam13896
    Location:443 → 712
    Glyco_transf_49; Glycosyl-transferase for dystroglycan
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6PA90.1 GenPept UniProtKB/Swiss-Prot:Q6PA90

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