fmo2.L flavin containing dimethylaniline monooxygenase 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: fmo2.L
Official Full Name: flavin containing dimethylaniline monooxygenase 2 L homeolog
Primary source: Xenbase:XB-GENE-6254926
Locus tag: XELAEV_18023397mg
See related: EnsemblRapid:ENSXLAG00005012453 AllianceGenome:Xenbase:XB-GENE-6254926
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: fmo2
Summary: Predicted to enable nucleotide binding activity and oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen. Predicted to be located in endoplasmic reticulum membrane. Orthologous to human FMO2 (flavin containing dimethylaniline monoxygenase 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 4L

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (104090861..104107461, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (98816061..98832609, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables N,N-dimethylaniline monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables NADP binding	IEA Inferred from Electronic Annotation more info
enables flavin adenine dinucleotide binding	IEA Inferred from Electronic Annotation more info
enables hypotaurine monooxygenase activity	IEA Inferred from Electronic Annotation more info
enables monooxygenase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: flavin containing dimethylaniline monooxygenase 2 L homeolog

Names: flavin containing monooxygenase 2 (non-functional); flavin containing monooxygenase 2 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089978.1 → NP_001083447.1 flavin containing dimethylaniline monooxygenase 2 L homeolog

See identical proteins and their annotated locations for NP_001083447.1

Status: PROVISIONAL

Source sequence(s)

BC060427

UniProtKB/TrEMBL

A0A974HPI8, Q6PA74

Related

ENSXLAP00005036525.1, ENSXLAT00005037434.1

Conserved Domains (1) summary

pfam00743
Location:2 → 509

FMO-like; Flavin-binding monooxygenase-like

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

104090861..104107461 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041589218.1 → XP_041445152.1 flavin containing dimethylaniline monooxygenase 2 L homeolog isoform X1

UniProtKB/TrEMBL

A0A8J1MTR2

Conserved Domains (1) summary

COG2072
Location:1 → 266

CzcO; Predicted flavoprotein CzcO associated with the cation diffusion facilitator CzcD [Inorganic ion transport and metabolism]