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cldn18.L claudin 18 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398928, updated on 4-Nov-2024

Summary

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Official Symbol
cldn18.L
Official Full Name
claudin 18 L homeolog
Primary source
Xenbase:XB-GENE-991174
Locus tag
XELAEV_18027968mg
See related
EnsemblRapid:ENSXLAG00005013184 AllianceGenome:Xenbase:XB-GENE-991174
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
cldn18; claudin-18
Summary
Predicted to enable structural molecule activity. Predicted to act upstream of or within bicellular tight junction assembly and cell adhesion. Predicted to be located in bicellular tight junction and plasma membrane. Orthologous to human CLDN18 (claudin 18). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See cldn18.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (142160394..142180750, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (131080516..131091373, complement)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene alpha-1,4-N-acetylglucosaminyltransferase Neighboring gene DAZ interacting zinc finger protein 1-like L homeolog Neighboring gene SRY-box 14 L homeolog Neighboring gene interleukin-20 receptor subunit beta

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68719

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within bicellular tight junction assembly IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell adhesion IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
claudin 18 L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089974.1 → NP_001083443.1  claudin 18 L homeolog

    See identical proteins and their annotated locations for NP_001083443.1

    Status: PROVISIONAL

    Source sequence(s)
    BC060425
    UniProtKB/TrEMBL
    Q6PA76
    Conserved Domains (1) summary
    cl21598
    Location:7 → 198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    142160394..142180750 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562121.1 → XP_041418055.1  claudin 18 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A1L8GBU4, A0A974CYI9
    Related
    ENSXLAP00005038878.1, ENSXLAT00005039799.1
    Conserved Domains (1) summary
    cl21598
    Location:7 → 198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  2. XM_041562120.1 → XP_041418054.1  claudin 18 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1KP94
    Related
    ENSXLAP00005038872.1, ENSXLAT00005039794.1
    Conserved Domains (1) summary
    cl21598
    Location:15 → 198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
Nucleotide Protein Strain
Heading Accession and Version

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