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acap2.L ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398916, updated on 4-Nov-2024

Summary

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Official Symbol
acap2.L
Official Full Name
ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 L homeolog
Primary source
Xenbase:XB-GENE-990717
Locus tag
XELAEV_18027521mg
See related
EnsemblRapid:ENSXLAG00005026665 AllianceGenome:Xenbase:XB-GENE-990717
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
acap2; centb2; cnt-b2
Summary
Predicted to enable GTPase activator activity and metal ion binding activity. Predicted to be located in endosome membrane. Orthologous to human ACAP2 (ArfGAP with coiled-coil, ankyrin repeat and PH domains 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See acap2.L in Genome Data Viewer
Location:
chromosome: 5L
Exon count:
25
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (113199703..113256565)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (102504901..102561464)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene 3-hydroxybutyrate dehydrogenase, type 1 A L homeolog Neighboring gene 3-hydroxybutyrate dehydrogenase, type 1 B L homeolog Neighboring gene protein phosphatase 1 regulatory inhibitor subunit 2 L homeolog Neighboring gene U2 spliceosomal RNA Neighboring gene family with sequence similarity 43 member A L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68712

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome membrane IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2; uncharacterized protein LOC398916

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    113199703..113256565
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041563303.1 → XP_041419237.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8J1KPI7, Q6PA21
    Conserved Domains (3) summary
    cd07638
    Location:18 → 217
    BAR_ACAP2; The Bin/Amphiphysin/Rvs (BAR) domain of ArfGAP with Coiled-coil, ANK repeat and PH domain containing protein 2
    cd13250
    Location:269 → 372
    PH_ACAP; ArfGAP with coiled-coil, ankyrin repeat and PH domains Pleckstrin homology (PH) domain
    cd08851
    Location:404 → 519
    ArfGap_ACAP2; ArfGAP domain of ACAP2 (ArfGAP with Coiled-coil, ANK repeat and PH domains 2)

  2. XM_018261771.2 → XP_018117260.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8J0V833
    Related
    ENSXLAP00005080357.1, ENSXLAT00005081950.1

  3. XM_018261769.2 → XP_018117258.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A1L8G9W2, A0A974CWL2
    Related
    ENSXLAP00005080034.1, ENSXLAT00005081627.1

  4. XM_018261770.2 → XP_018117259.1  arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A1L8GAF4, A0A974CXP1
    Related
    ENSXLAP00005081006.1, ENSXLAT00005082618.1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001089951.1: Suppressed sequence

    Description
    NM_001089951.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version

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