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slco1a2.L solute carrier organic anion transporter family member 1A2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398783, updated on 4-Nov-2024

Summary

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Official Symbol
slco1a2.L
Official Full Name
solute carrier organic anion transporter family member 1A2 L homeolog
Primary source
Xenbase:XB-GENE-6255431
Locus tag
XELAEV_18016595mg
See related
EnsemblRapid:ENSXLAG00005007441 AllianceGenome:Xenbase:XB-GENE-6255431
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
oatp; oatp-a; oatp1a2; slc21a3; slco1a2
Summary
Predicted to enable bile acid transmembrane transporter activity and sodium-independent organic anion transmembrane transporter activity. Predicted to act upstream of or within several processes, including bile acid and bile salt transport; monoatomic ion transport; and sodium-independent organic anion transport. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See slco1a2.L in Genome Data Viewer
Location:
chromosome: 3L
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 3L NC_054375.1 (792330..803519)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 3L NC_030728.1 (798167..809604)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016718071.1 (222..676)

Chromosome 3L - NC_054375.1Genomic Context describing neighboring genes Neighboring gene solute carrier organic anion transporter family member 1C1 L homeolog Neighboring gene solute carrier organic anion transporter family member 1B3 L homeolog Neighboring gene cytidine monophosphate N-acetylneuraminic acid synthetase L homeolog Neighboring gene ATP binding cassette subfamily C member 9 L homeolog Neighboring gene potassium inwardly rectifying channel subfamily J member 8 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC68666

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables bile acid transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables sodium-independent organic anion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within bile acid and bile salt transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within sodium-independent organic anion transport IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC398783

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089702.2 → NP_001083171.1  uncharacterized protein LOC398783

    See identical proteins and their annotated locations for NP_001083171.1

    Status: PREDICTED

    Source sequence(s)
    BC060021
    UniProtKB/TrEMBL
    A0A974DC23, Q6PAW3
    Related
    ENSXLAP00005021183.1, ENSXLAT00005021843.1
    Conserved Domains (3) summary
    cd06174
    Location:23 → 382
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    cd01330
    Location:436 → 488
    KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
    pfam03137
    Location:21 → 601
    OATP; Organic Anion Transporter Polypeptide (OATP) family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    792330..803519
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041585008.1 → XP_041440942.1  uncharacterized protein LOC398783 isoform X1

    UniProtKB/TrEMBL
    A0A8J1MGV1, A0A974DC23
    Conserved Domains (1) summary
    cl28910
    Location:18 → 542
    MFS; Major Facilitator Superfamily
Nucleotide Protein Strain
Heading Accession and Version

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