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agtr1.L angiotensin II receptor type 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398763, updated on 17-Aug-2024

Summary

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Official Symbol
agtr1.L
Official Full Name
angiotensin II receptor type 1 L homeolog
Primary source
Xenbase:XB-GENE-865228
Locus tag
XELAEV_18027747mg
See related
EnsemblRapid:ENSXLAG00005017600
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
xAT; agtr1; agtr1-a; agtr1-b
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Genomic context

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Location:
chromosome: 5L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5L NC_054379.1 (130502174..130569720)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5L NC_030732.1 (119783623..119820516)

Chromosome 5L - NC_054379.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121393815 Neighboring gene uncharacterized LOC108716365 Neighboring gene carboxypeptidase B Neighboring gene uncharacterized LOC733324

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular cloning, sequencing and functional expression of an amphibian angiotensin II receptor. Ji H, et al. Biochem Biophys Res Commun, 1993 Jul 30. PMID 7688227
  2. Isolation and characterization of two alternatively spliced complementary DNAs encoding a Xenopus laevis angiotensin II receptor. Nishimatsu S, et al. Biochim Biophys Acta, 1994 Aug 2. PMID 7519446
  3. Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells. Ashry O, et al. Respir Physiol Neurobiol, 2014 May 1. PMID 24530803
  4. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. transcripts for the ANGII receptor type 1 (ATR1) were detected in lungs of Xenopus laevis
    Title: Evidence for expression and function of angiotensin II receptor type 1 in pulmonary epithelial cells.
Submit: New GeneRIF Correction

General gene information

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Homology

Clone Names

  • MGC68752

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables angiotensin receptor activity IDA
Inferred from Direct Assay
more info
 PubMed 
enables angiotensin type I receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables angiotensin type II receptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within phospholipase C-activating angiotensin-activated signaling pathway IDA
Inferred from Direct Assay
more info
 PubMed 
acts_upstream_of_or_within regulation of vasoconstriction IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
type-1 angiotensin II receptor A
Names
AT1
AT1-1
Type-1-like angiotensin II receptor 1
angiotensin 2 receptor, type 1 L homeolog
angiotensin 2 receptor, type 1-A
angiotensin II receptor, type 1-A
angiotensin II type-1 receptor 1
angiotensin type 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089663.1 → NP_001083132.1  type-1 angiotensin II receptor A

    Status: PROVISIONAL

    Source sequence(s)
    BC059993
    UniProtKB/Swiss-Prot
    P32303
    Related
    ENSXLAP00005051959.1, ENSXLAT00005053121.1
    Conserved Domains (2) summary
    pfam00001
    Location:46 → 301
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:38 → 261
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    130502174..130569720
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041562117.1 → XP_041418051.1  type-1 angiotensin II receptor A isoform X1

    UniProtKB/Swiss-Prot
    P32303, Q6PAZ1, Q91383
    UniProtKB/TrEMBL
    A0A1L8GB00, A0A974CY87
    Conserved Domains (1) summary
    cd15192
    Location:30 → 312
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors

  2. XM_018261751.2 → XP_018117240.1  type-1 angiotensin II receptor A isoform X1

    UniProtKB/Swiss-Prot
    P32303, Q6PAZ1, Q91383
    UniProtKB/TrEMBL
    A0A1L8GB00, A0A974CY87
    Related
    ENSXLAP00005051952.1, ENSXLAT00005053114.1
    Conserved Domains (1) summary
    cd15192
    Location:30 → 312
    7tmA_AT1R; type 1 angiotensin II receptor, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P32303.2 GenPept UniProtKB/Swiss-Prot:P32303

Gene LinkOut

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