gda.L guanine deaminase L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gda.L
Official Full Name: guanine deaminase L homeolog
Primary source: Xenbase:XB-GENE-987047
Locus tag: XELAEV_18006888mg
See related: AllianceGenome:Xenbase:XB-GENE-987047
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: gda
Summary: Predicted to enable guanine deaminase activity and zinc ion binding activity. Predicted to act upstream of or within guanine catabolic process. Predicted to be located in cytosol. Is expressed in urinary system. Orthologous to human GDA (guanine deaminase). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 1L

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	1L	NC_054371.1 (141232180..141255972)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	1L	NC_030724.1 (128818522..128842364)

Chromosome 1L - NC_054371.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables guanine deaminase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within guanine catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within guanine metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: guanine deaminase L homeolog

NP_001083074.1

EC 3.5.4.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089605.1 → NP_001083074.1 guanine deaminase L homeolog

See identical proteins and their annotated locations for NP_001083074.1

Status: PROVISIONAL

Source sequence(s)

BC082390

UniProtKB/TrEMBL

Q641E7, Q6PE97

Conserved Domains (1) summary

cl00281
Location:8 → 359

metallo-dependent_hydrolases; Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a ...