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PGRP-SB1 Peptidoglycan recognition protein SB1 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 39870, updated on 18-Sep-2024

Summary

Official Symbol
PGRP-SB1provided by FlyBase
Official Full Name
Peptidoglycan recognition protein SB1provided by FlyBase
Primary source
FLYBASE:FBgn0043578
Locus tag
Dmel_CG9681
See related
AllianceGenome:FB:FBgn0043578
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
142657_at; CG9681; Dmel\CG9681; PGRP SB1; PGRP-SB
Summary
Enables N-acetylmuramoyl-L-alanine amidase activity. Predicted to be involved in peptidoglycan catabolic process. Located in extracellular region. Is expressed in adult head. Orthologous to human PGLYRP4 (peptidoglycan recognition protein 4). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

See PGRP-SB1 in Genome Data Viewer
Location:
73C1-73C1; 3-44 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (16727299..16727989, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (16720399..16721089, complement)

Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Peptidoglycan recognition protein SB2 Neighboring gene Dead box protein 73D Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables N-acetylmuramoyl-L-alanine amidase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables N-acetylmuramoyl-L-alanine amidase activity IEA
Inferred from Electronic Annotation
more info
 
enables N-acetylmuramoyl-L-alanine amidase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
enables peptidoglycan binding IEA
Inferred from Electronic Annotation
more info
 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in defense response to bacterium IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 
involved_in innate immune response NAS
Non-traceable Author Statement
more info
PubMed 
involved_in peptidoglycan catabolic process IEA
Inferred from Electronic Annotation
more info
 
involved_in peptidoglycan catabolic process ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
involved_in peptidoglycan catabolic process NAS
Non-traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular region IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
peptidoglycan recognition protein SB1
Names
CG9681-PA
PGRP-SB1-PA
Peptidoglycan-recognition protein-SB1 precursor
peptidoglycan receptor protein SB1
peptidoglycan recognition
protein-like
NP_648917.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_037436.4 Reference assembly

    Range
    16727299..16727989 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_140660.4NP_648917.1  peptidoglycan recognition protein SB1 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_648917.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    A0FIQ1, A0JQ53, Q4V3W6, Q70PY2, Q70PY3, Q70PY4, Q70PY7, Q9VV97
    Related
    FBpp0075107
    Conserved Domains (1) summary
    smart00701
    Location:25167
    PGRP; Animal peptidoglycan recognition proteins homologous to Bacteriophage T3 lysozyme