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atp6v0c.L ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398647, updated on 4-Nov-2024

Summary

Official Symbol
atp6v0c.L
Official Full Name
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog
Primary source
Xenbase:XB-GENE-981796
Locus tag
XELAEV_18045397mg
See related
EnsemblRapid:ENSXLAG00005019145 AllianceGenome:Xenbase:XB-GENE-981796
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
atpl; vatl; vma3; atp6c; atp6l; xduct; ductin; atp6v0c
Summary
Predicted to enable proton-transporting ATPase activity, rotational mechanism. Predicted to act upstream of or within proton transmembrane transport. Predicted to be located in clathrin-coated vesicle membrane; synaptic vesicle membrane; and vacuolar membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Is expressed in dermal system and nervous system. Human ortholog(s) of this gene implicated in early-onset epilepsy 3 and thyroid gland carcinoma. Orthologous to human ATP6V0C (ATPase H+ transporting V0 subunit c). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See atp6v0c.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (115297403..115308445)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (104691041..104702084)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108701616 Neighboring gene TBC1 domain family member 24 L homeolog Neighboring gene amidohydrolase domain containing 2 L homeolog Neighboring gene chromosome 9 C8orf33 homolog L homeolog

Genomic regions, transcripts, and products

General gene information

Clone Names

  • MGC64475

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables proton-transporting ATPase activity, rotational mechanism IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within proton transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in clathrin-coated vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
part_of proton-transporting V-type ATPase, V0 domain IEA
Inferred from Electronic Annotation
more info
 
located_in synaptic vesicle membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuolar membrane IEA
Inferred from Electronic Annotation
more info
 
located_in vacuole IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog
NP_001082675.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089206.1NP_001082675.1  ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c L homeolog

    See identical proteins and their annotated locations for NP_001082675.1

    Status: PROVISIONAL

    Source sequence(s)
    BC054258
    UniProtKB/TrEMBL
    A0A974H481, Q7SYU8
    Related
    ENSXLAP00005056521.1, ENSXLAT00005057758.1
    Conserved Domains (2) summary
    TIGR01100
    Location:14119
    V_ATP_synt_C; vacuolar ATP synthase 16 kDa proteolipid subunit
    pfam00137
    Location:94154
    ATP-synt_C; ATP synthase subunit C

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    115297403..115308445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)