U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

brd7.L bromodomain containing 7 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398590, updated on 4-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
brd7.L
Official Full Name
bromodomain containing 7 L homeolog
Primary source
Xenbase:XB-GENE-1017012
Locus tag
XELAEV_18022463mg
See related
EnsemblRapid:ENSXLAG00005006117 AllianceGenome:Xenbase:XB-GENE-1017012
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
brd7
Summary
Predicted to enable lysine-acetylated histone binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human BRD7 (bromodomain containing 7). [provided by Alliance of Genome Resources, Nov 2024]
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See brd7.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
16
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (39497024..39521210, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (36989701..37013987, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene terminal nucleotidyltransferase 4B L homeolog Neighboring gene adenylate cyclase 7 L homeolog Neighboring gene nucleoporin 93kDa L homeolog Neighboring gene uncharacterized LOC121403001

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. Kırlı K, et al. Elife, 2015 Dec 17. PMID 26673895, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables lysine-acetylated histone binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

Go to the top of the page Help
Preferred Names
bromodomain-containing protein 7
Names
nuclear transcriptor-like protein

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001089123.1 → NP_001082592.1  bromodomain-containing protein 7

    See identical proteins and their annotated locations for NP_001082592.1

    Status: PROVISIONAL

    Source sequence(s)
    BC070751
    UniProtKB/TrEMBL
    A0A974D544, Q802C4
    Related
    ENSXLAP00005018362.1, ENSXLAT00005018659.1
    Conserved Domains (2) summary
    cd05513
    Location:138 → 235
    Bromo_brd7_like; Bromodomain, brd7_like subgroup. The BRD7 gene encodes a nuclear protein that has been shown to inhibit cell growth and the progression of the cell cycle by regulating cell-cycle genes at the transcriptional level. BRD7 has been identified as a gene ...
    pfam12024
    Location:289 → 516
    DUF3512; Domain of unknown function (DUF3512)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    39497024..39521210 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.