klhl25.L kelch like family member 25 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: klhl25.L
Official Full Name: kelch like family member 25 L homeolog
Primary source: Xenbase:XB-GENE-964642
Locus tag: XELAEV_18018374mg
See related: EnsemblRapid:ENSXLAG00005021444
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: enc2; ENC-2; encr-2; klhl25; Xencr-2
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Genomic context

Location:: chromosome: 3L

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (117470964..117505563)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (102057322..102076801)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables ubiquitin-like ligase-substrate adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of fatty acid oxidation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within protein ubiquitination	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of translational initiation	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within ubiquitin-dependent protein catabolic process	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of Cul3-RING ubiquitin ligase complex	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: kelch-like protein 25

Names: ectoderm neural cortex related-2; ectoderm-neural cortex protein 2; kelch-like 25; kelch-like family member 25

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089103.1 → NP_001082572.1 kelch-like protein 25

See identical proteins and their annotated locations for NP_001082572.1

Status: PROVISIONAL

Source sequence(s)

BC076781

UniProtKB/Swiss-Prot

Q6DFF7

UniProtKB/TrEMBL

A0A974DE45

Related

ENSXLAP00005062985.1, ENSXLAT00005064438.1

Conserved Domains (7) summary

smart00612
Location:539 → 585

Kelch; Kelch domain

PHA03098
Location:37 → 566

PHA03098; kelch-like protein; Provisional

sd00038
Location:330 → 374

Kelch; KELCH repeat [structural motif]

pfam00651
Location:36 → 140

BTB; BTB/POZ domain

pfam01344
Location:329 → 374

Kelch_1; Kelch motif

pfam07707
Location:149 → 250

BACK; BTB And C-terminal Kelch

pfam13415
Location:445 → 490

Kelch_3; Galactose oxidase, central domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

117470964..117505563

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041585006.1 → XP_041440940.1 kelch-like protein 25 isoform X1

UniProtKB/TrEMBL

A0A8J1MIQ7

Related

ENSXLAP00005062996.1, ENSXLAT00005064449.1

Conserved Domains (4) summary

PHA03098
Location:59 → 588

PHA03098; kelch-like protein; Provisional

sd00038
Location:352 → 396

Kelch; KELCH repeat [structural motif]

cd18254
Location:46 → 173

BTB_POZ_KLHL25; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in Kelch-like protein 25 (KLHL25)

cl28903
Location:166 → 264

BACK; BACK (BTB and C-terminal Kelch) domain