iws1.S IWS1, SUPT6H interacting protein S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: iws1.S
Official Full Name: IWS1, SUPT6H interacting protein S homeolog
Primary source: Xenbase:XB-GENE-6256046
Locus tag: XELAEV_18029873mg
See related: EnsemblRapid:ENSXLAG00005025780 AllianceGenome:Xenbase:XB-GENE-6256046
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: iws1; iws1-a; iws1l-a; flj10006
Summary: Predicted to act upstream of or within RNA splicing; mRNA processing; and poly(A)+ mRNA export from nucleus. Predicted to be located in nucleus. Orthologous to human IWS1 (interacts with SUPT6H, CTD assembly factor 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 5S

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5S	NC_054380.1 (113217981..113245281)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5S	NC_030733.1 (106460928..106487634)

Chromosome 5S - NC_054380.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by Xenbase

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mRNA transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within poly(A)+ mRNA export from nucleus	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein IWS1 homolog A

Names: IWS1 homolog; IWS1-like protein A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089061.1 → NP_001082530.1 protein IWS1 homolog A

See identical proteins and their annotated locations for NP_001082530.1

Status: PROVISIONAL

Source sequence(s)

BC077238

UniProtKB/Swiss-Prot

Q6DE96, Q8AVS0

UniProtKB/TrEMBL

A0A974HI72

Related

ENSXLAP00005076963.1, ENSXLAT00005078554.1

Conserved Domains (2) summary

PHA03151
Location:105 → 343

PHA03151; hypothetical protein; Provisional

cl00146
Location:543 → 742

TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme