hnrnpu.L heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: hnrnpu.L
Official Full Name: heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) L homeolog
Primary source: Xenbase:XB-GENE-17345613
Locus tag: XELAEV_18026704mg
See related: EnsemblRapid:ENSXLAG00005018063
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: hnrpu; saf-a; hnrnpu
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Genomic context

Location:: chromosome: 5L

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (44872358..44885025, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (43719858..43732742, complement)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables RNA polymerase II C-terminal domain binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables TFIIH-class transcription factor complex binding	IEA Inferred from Electronic Annotation more info
enables poly(C) RNA binding	IEA Inferred from Electronic Annotation more info
enables poly(G) binding	IEA Inferred from Electronic Annotation more info
enables pre-mRNA binding	IEA Inferred from Electronic Annotation more info
enables promoter-specific chromatin binding	IEA Inferred from Electronic Annotation more info
enables ribonucleoprotein complex binding	IEA Inferred from Electronic Annotation more info
enables snRNA binding	IEA Inferred from Electronic Annotation more info
enables transcription corepressor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within CRD-mediated mRNA stabilization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within RNA localization to chromatin	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of telomere maintenance via telomerase	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within negative regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of attachment of mitotic spindle microtubules to kinetochore	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of chromatin organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of mitotic spindle assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of CRD-mediated mRNA stability complex	IEA Inferred from Electronic Annotation more info
part_of catalytic step 2 spliceosome	IEA Inferred from Electronic Annotation more info
located_in centrosome	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic ribonucleoprotein granule	IEA Inferred from Electronic Annotation more info
located_in inactive sex chromosome	IEA Inferred from Electronic Annotation more info
located_in kinetochore	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in mitotic spindle microtubule	IEA Inferred from Electronic Annotation more info
located_in mitotic spindle midzone	IEA Inferred from Electronic Annotation more info
located_in nuclear chromosome	IEA Inferred from Electronic Annotation more info
located_in nuclear matrix	IEA Inferred from Electronic Annotation more info
located_in nuclear speck	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
part_of telomerase holoenzyme complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: heterogeneous nuclear ribonucleoprotein U

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089005.2 → NP_001082474.2 heterogeneous nuclear ribonucleoprotein U

Status: PROVISIONAL

Source sequence(s)

BC046700, BC072816

UniProtKB/TrEMBL

A0A8J0PSM9

Related

ENSXLAP00005053363.1, ENSXLAT00005054536.1

Conserved Domains (6) summary

smart00513
Location:7 → 41

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

pfam04959
Location:676 → 743

ARS2; Arsenite-resistance protein 2

pfam13671
Location:448 → 591

AAA_33; AAA domain

pfam15502
Location:676 → 760

MPLKIP; M-phase-specific PLK1-interacting protein

cd12884
Location:237 → 413

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

cl17190
Location:448 → 584

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054379.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

44872358..44885025 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041562108.1 → XP_041418042.1 heterogeneous nuclear ribonucleoprotein U isoform X2

UniProtKB/TrEMBL

A0A8J1KL44

Related

ENSXLAP00005053333.1, ENSXLAT00005054505.1

Conserved Domains (3) summary

smart00513
Location:7 → 41

SAP; Putative DNA-binding (bihelical) motif predicted to be involved in chromosomal organisation

cd12884
Location:237 → 413

SPRY_hnRNP; SPRY domain in heterogeneous nuclear ribonucleoprotein U-like (hnRNP) protein 1

cl17190
Location:448 → 584

NK; Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates ...
XM_018261737.2 → XP_018117226.1 heterogeneous nuclear ribonucleoprotein U isoform X1

UniProtKB/TrEMBL

A0A1L8G7R5, A0A974HJ01

Related

ENSXLAP00005053351.1, ENSXLAT00005054523.1