gtf2f1.L general transcription factor IIF subunit 1 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: gtf2f1.L
Official Full Name: general transcription factor IIF subunit 1 L homeolog
Primary source: Xenbase:XB-GENE-974839
Locus tag: XELAEV_18019102mg
See related: EnsemblRapid:ENSXLAG00005002029
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: rap74; gtf2f1
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Genomic context

Location:: chromosome: 3L

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (150459290..150479444)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	3L	NC_030728.1 (133558930..133583318)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II general transcription initiation factor activity	IEA Inferred from Electronic Annotation more info
enables TFIIF-class transcription factor complex binding	IEA Inferred from Electronic Annotation more info
enables promoter-specific chromatin binding	ISS Inferred from Sequence or Structural Similarity more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of protein binding	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within positive regulation of transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transcription initiation at RNA polymerase II promoter	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription factor TFIIF complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: general transcription factor IIF subunit 1

Names: RAP74 subunit of transcription factor IIF; TFIIF-alpha; general transcription factor IIF, polypeptide 1, 74kDa; transcription initiation factor IIF subunit alpha; transcription initiation factor RAP74

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088789.1 → NP_001082258.1 general transcription factor IIF subunit 1

See identical proteins and their annotated locations for NP_001082258.1

Status: PROVISIONAL

Source sequence(s)

BC070569

UniProtKB/Swiss-Prot

Q04870, Q6IRR6

UniProtKB/TrEMBL

A0A974DEV9, Q8JGL7

Related

ENSXLAP00005006108.1, ENSXLAT00005006214.1

Conserved Domains (2) summary

cd00240
Location:12 → 172

TFIIFa; Transcription initiation factor IIF, alpha subunit, N-terminal region of RAP74. Subunit of transcription initiation complex involved in initiation, elongation and promoter escape.Tetramer of 2 alpha and 2 beta TFIIF subunits interacts directly with RNA ...

pfam05793
Location:2 → 524

TFIIF_alpha; Transcription initiation factor IIF, alpha subunit (TFIIF-alpha)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054375.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

150459290..150479444

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018250819.2 → XP_018106308.1 general transcription factor IIF subunit 1 isoform X1

UniProtKB/Swiss-Prot

Q04870, Q6IRR6

UniProtKB/TrEMBL

A0A974DEV9, Q8JGL7
XM_018250821.2 → XP_018106310.1 general transcription factor IIF subunit 1 isoform X2

UniProtKB/TrEMBL

A0A8J0UNA9, Q8JGL7
XM_018250820.2 → XP_018106309.1 general transcription factor IIF subunit 1 isoform X1

UniProtKB/Swiss-Prot

Q04870, Q6IRR6

UniProtKB/TrEMBL

A0A974DEV9, Q8JGL7