dlat.L dihydrolipoamide S-acetyltransferase L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: dlat.L
Official Full Name: dihydrolipoamide S-acetyltransferase L homeolog
Primary source: Xenbase:XB-GENE-982540
Locus tag: XELAEV_18035497mg
See related: EnsemblRapid:ENSXLAG00005012310
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: dlat; dlat.S
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Genomic context

Location:: chromosome: 7L

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7L	NC_054383.1 (86349534..86372956)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7L	NC_030736.1 (77758906..77782338)

Chromosome 7L - NC_054383.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables dihydrolipoyllysine-residue acetyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within acetyl-CoA biosynthetic process from pyruvate	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within pyruvate metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in mitochondrial matrix	IEA Inferred from Electronic Annotation more info
part_of pyruvate dehydrogenase complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: dihydrolipoamide S-acetyltransferase L homeolog

Names: dihydrolipoamide S-acetyltransferase S homeolog; dihydrolipoamide acetyltransferase

NP_001082239.1

EC 2.3.1.12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088770.1 → NP_001082239.1 dihydrolipoamide S-acetyltransferase L homeolog

See identical proteins and their annotated locations for NP_001082239.1

Status: PROVISIONAL

Source sequence(s)

BC124833

UniProtKB/TrEMBL

A0A974CFW0, A0AUS4, Q8JHX7

Related

ENSXLAP00005036084.1, ENSXLAT00005036985.1

Conserved Domains (5) summary

cd06849
Location:73 → 146

lipoyl_domain; Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid ...

TIGR01349
Location:197 → 628

PDHac_trf_mito; pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form

pfam00198
Location:416 → 628

2-oxoacid_dh; 2-oxoacid dehydrogenases acyltransferase (catalytic domain)

pfam02817
Location:332 → 365

E3_binding; e3 binding domain

pfam12200
Location:293 → 345

DUF3597; Domain of unknown function (DUF3597)