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ackr3.L atypical chemokine receptor 3 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398310, updated on 4-Nov-2024

Summary

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Official Symbol
ackr3.L
Official Full Name
atypical chemokine receptor 3 L homeolog
Primary source
Xenbase:XB-GENE-939866
Locus tag
XELAEV_18044828mg
See related
EnsemblRapid:ENSXLAG00005021926 AllianceGenome:Xenbase:XB-GENE-939866
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
rdc1; ackr3; cxcr7; xcxcr7
Summary
Predicted to enable G protein-coupled receptor activity; chemokine binding activity; and coreceptor activity. Predicted to act upstream of or within G protein-coupled receptor signaling pathway; blood vessel morphogenesis; and chemotaxis. Predicted to be located in plasma membrane. Orthologous to human ACKR3 (atypical chemokine receptor 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See ackr3.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
3
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (83006744..83018975, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (72505938..72518176, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene collagen type VI alpha 3 chain L homeolog Neighboring gene COP9 signalosome subunit 8 L homeolog Neighboring gene IQ motif containing with AAA domain 1 L homeolog Neighboring gene ankyrin repeat and SOCS box containing 18 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Expression of xSDF-1α, xCXCR4, and xCXCR7 during gastrulation in Xenopus laevis. Mishra SK, et al. Int J Dev Biol, 2013. PMID 23585357
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
  
enables chemokine binding IEA
Inferred from Electronic Annotation
more info
  
enables coreceptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within angiogenesis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chemotaxis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within vasculogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
atypical chemokine receptor 3 L homeolog
Names
RDC1 like protein
chemokine (C-X-C motif) receptor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088767.1 → NP_001082236.1  atypical chemokine receptor 3 L homeolog

    See identical proteins and their annotated locations for NP_001082236.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ312935
    UniProtKB/TrEMBL
    A0A974BZ92, Q4KLW1, Q8QFR6
    Related
    ENSXLAP00005064445.1, ENSXLAT00005065959.1
    Conserved Domains (1) summary
    cd14987
    Location:49 → 334
    7tmA_ACKR3_CXCR7; CXC chemokine receptor 7, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    83006744..83018975 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575537.1 → XP_041431471.1  atypical chemokine receptor 3 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974BZ92, Q4KLW1, Q8QFR6
    Related
    ENSXLAP00005064436.1, ENSXLAT00005065950.1
    Conserved Domains (1) summary
    cd14987
    Location:49 → 334
    7tmA_ACKR3_CXCR7; CXC chemokine receptor 7, member of the class A family of seven-transmembrane G protein-coupled receptors
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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