mapt.L microtubule associated protein tau L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: mapt.L
Official Full Name: microtubule associated protein tau L homeolog
Primary source: Xenbase:XB-GENE-986953
Locus tag: XELAEV_18043331mg
See related: EnsemblRapid:ENSXLAG00005036820
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: tau; xtp; mapt
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Genomic context

Location:: chromosome: 9_10L

Exon count:: 17

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	9_10L	NC_054387.1 (6140614..6186224, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	9_10L	NC_030740.1 (6106930..6153069, complement)

Chromosome 9_10L - NC_054387.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Suppressing the expression of all tau isoforms disrupted only those neuronal microtubules containing class II beta-tubulin, and that boosting the expression of the largest 'big', but not the smallest, tau isoform enhanced neurite outgrowth.
Title: Microtubule-associated protein tau promotes neuronal class II β-tubulin microtubule formation and axon elongation in embryonic Xenopus laevis.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables microtubule binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within microtubule cytoskeleton organization	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neuron projection development	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: microtubule-associated protein tau

Names: microtubule-associated protein tau 402; microtubule-associated protein tau 464; microtubule-associated protein tau 611; microtubule-associated protein tau 688; tau-like protein; tau-like protein-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088761.1 → NP_001082230.1 microtubule-associated protein tau

See identical proteins and their annotated locations for NP_001082230.1

Status: PROVISIONAL

Source sequence(s)

AY032847

UniProtKB/TrEMBL

A0A0B5HH19, Q8JIW8

Conserved Domains (1) summary

pfam00418
Location:508 → 537

Tubulin-binding; Tau and MAP protein, tubulin-binding repeat

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

6140614..6186224 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_018234164.2 → XP_018089653.1 microtubule-associated protein tau isoform X4

UniProtKB/TrEMBL

A0A8J0TSS2, Q8JIW7

Related

ENSXLAP00005110424.1, ENSXLAT00005112637.1
XM_018234159.2 → XP_018089648.1 microtubule-associated protein tau isoform X2

UniProtKB/TrEMBL

A0A0B5HH19, A0A8J0TJ22
XM_018234160.2 → XP_018089649.1 microtubule-associated protein tau isoform X3

UniProtKB/TrEMBL

A0A0B5HH19, A0A8J0TRP8
XM_018234166.2 → XP_018089655.1 microtubule-associated protein tau isoform X5

UniProtKB/TrEMBL

A0A0B5HAV7, A0A8J0TTV1

Related

ENSXLAP00005110428.1, ENSXLAT00005112641.1
XM_041575535.1 → XP_041431469.1 microtubule-associated protein tau isoform X1

UniProtKB/TrEMBL

A0A0B5HH19, A0A8J1LQE4

Conserved Domains (2) summary

PHA03307
Location:184 → 523

PHA03307; transcriptional regulator ICP4; Provisional

TIGR00927
Location:34 → 228

2A1904; K+-dependent Na+/Ca+ exchanger
XM_041575534.1 → XP_041431468.1 microtubule-associated protein tau isoform X1

UniProtKB/TrEMBL

A0A0B5HH19, A0A8J1LQE4

Conserved Domains (2) summary

PHA03307
Location:184 → 523

PHA03307; transcriptional regulator ICP4; Provisional

TIGR00927
Location:34 → 228

2A1904; K+-dependent Na+/Ca+ exchanger