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sp5l.S Sp5 transcription factor-like S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398277, updated on 4-Nov-2024

Summary

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Official Symbol
sp5l.S
Official Full Name
Sp5 transcription factor-like S homeolog
Primary source
Xenbase:XB-GENE-6485591
Locus tag
XELAEV_18015944mg
See related
AllianceGenome:Xenbase:XB-GENE-6485591
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
sp5l; spr2; XSpr2; spr-2; gli1-2; gli1.2; xspr-2
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Is expressed in ectoderm; mesoderm; and nervous system. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See sp5l.S in Genome Data Viewer
Location:
chromosome: 2S
Exon count:
2
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2S NC_054374.1 (132778174..132782227, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2S NC_030727.1 (123765390..123769488, complement)

Chromosome 2S - NC_054374.1Genomic Context describing neighboring genes Neighboring gene deltex E3 ubiquitin ligase 3 S homeolog Neighboring gene Rho guanine nucleotide exchange factor 25 S homeolog Neighboring gene solute carrier family 26 member 10 S homeolog Neighboring gene beta-1,4-N-acetyl-galactosaminyl transferase 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. XSPR-1 and XSPR-2, novel Sp1 related zinc finger containing genes, are dynamically expressed during Xenopus embryogenesis. Ossipova O, et al. Mech Dev, 2002 Jul. PMID 12049774
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
Sp5 transcription factor-like S homeolog
Names
GLI family zinc finger 1, gene 2
Sp1-like zinc-finger protein XSPR-2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088717.1 → NP_001082186.1  Sp5 transcription factor-like S homeolog

    See identical proteins and their annotated locations for NP_001082186.1

    Status: PROVISIONAL

    Source sequence(s)
    AY062263
    UniProtKB/TrEMBL
    Q4QR65, Q8UUU4
    Conserved Domains (4) summary
    COG5048
    Location:193 → 264
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:183 → 202
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00096
    Location:208 → 232
    zf-C2H2; Zinc finger, C2H2 type
    pfam13465
    Location:224 → 247
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    132778174..132782227 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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