spdyc.L speedy/RINGO cell cycle regulator family member C L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: spdyc.L
Official Full Name: speedy/RINGO cell cycle regulator family member C L homeolog
Primary source: Xenbase:XB-GENE-5886179
Locus tag: XELAEV_18022158mg
See related: EnsemblRapid:ENSXLAG00005018080
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ls27; spy1; spdy1; spdyc; ringo2; spdya-B; spdyc-a; spdyc-b
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 4L

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	4L	NC_054377.1 (24731524..24740127, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	4L	NC_030730.1 (23183482..23192156, complement)

Chromosome 4L - NC_054377.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

XRINGO-activated CDKs can phosphorylate specific residues in the regulatory domain of Myt1.
Title: Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation.
We show that the synthesis of RINGO/Spy, an atypical activator of cyclin-dependent kinases (cdks), is necessary for CPEB-directed polyadenylation.
Title: Regulated Pumilio-2 binding controls RINGO/Spy mRNA translation and CPEB activation.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cyclin binding	ISS Inferred from Sequence or Structural Similarity more info
enables protein kinase binding	IEA Inferred from Electronic Annotation more info
enables protein kinase binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within G2/MI transition of meiotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within meiotic cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within oocyte maturation	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within oocyte maturation	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of MAPK cascade	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within positive regulation of cyclin-dependent protein serine/threonine kinase activity	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within positive regulation of cyclin-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of meiotic cell cycle	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: speedy protein 1-B

Names: Protein Ls27; RINGO-B; XSpy1-B; p33 ringo; p33 ringo-B; rapid inducer of G2/M progression in oocytes B; speedy C; spy1-B; xRINGO-B

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088507.1 → NP_001081976.1 speedy protein 1-B

See identical proteins and their annotated locations for NP_001081976.1

Status: PROVISIONAL

Source sequence(s)

AJ133500

UniProtKB/Swiss-Prot

Q0IH64, Q4V879, Q6GR53, Q9PWR2, Q9YGL1

UniProtKB/TrEMBL

A0A974HN61

Related

ENSXLAP00005053356.1, ENSXLAT00005054528.1

Conserved Domains (1) summary

pfam11357
Location:62 → 192

Spy1; Cell cycle regulatory protein

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

24731524..24740127 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)