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mybl2.S MYB proto-oncogene like 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398085, updated on 4-Nov-2024

Summary

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Official Symbol
mybl2.S
Official Full Name
MYB proto-oncogene like 2 S homeolog
Primary source
Xenbase:XB-GENE-982423
Locus tag
XELAEV_18046595mg
See related
EnsemblRapid:ENSXLAG00005035722 AllianceGenome:Xenbase:XB-GENE-982423
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
bmyb; myb1; mybl2; XB-Myb
Summary
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to act upstream of or within mitotic cell cycle and positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in anatomical system; ectoderm; and pharyngeal arch. Orthologous to human MYBL2 (MYB proto-oncogene like 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mybl2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
15
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (33932004..33951801)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (28436997..28457705)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene L3MBTL1, histone methyl-lysine binding protein S homeolog Neighboring gene uncharacterized LOC121398978 Neighboring gene uncharacterized LOC121399185 Neighboring gene protein tyrosine phosphatase receptor type T S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Regulation of DNA binding activity and nuclear transport of B-Myb in Xenopus oocytes. Humbert-Lan G, et al. J Biol Chem, 1999 Apr 9. PMID 10187816
  2. Molecular cloning, expression and in vitro functional characterization of Myb-related proteins in Xenopus. Bouwmeester T, et al. Mech Dev, 1992 Mar. PMID 1606020
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
myb-related protein B
Names
B-Myb
XMYB1
myb-like protein 2
myb-related protein 1
v-myb avian myeloblastosis viral oncogene homolog-like 2 S homeolog
v-myb myeloblastosis viral oncogene homolog-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    33932004..33951801
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018237325.2 → XP_018092814.1  myb-related protein B isoform X1

    UniProtKB/TrEMBL
    A0A8J0TYT2, Q6NRE6
    Related
    ENSXLAP00005106910.1, ENSXLAT00005109023.1

  2. XM_018237326.2 → XP_018092815.1  myb-related protein B isoform X2

    UniProtKB/Swiss-Prot
    P52551
    UniProtKB/TrEMBL
    A0A8J0U0E5

  3. XM_018237327.2 → XP_018092816.1  myb-related protein B isoform X3

    UniProtKB/TrEMBL
    A0A8J0TXG0, Q6NRE6
    Related
    ENSXLAP00005106890.1, ENSXLAT00005109002.1

  4. XM_018237328.2 → XP_018092817.1  myb-related protein B isoform X4

    UniProtKB/Swiss-Prot
    P52551
    UniProtKB/TrEMBL
    A0A8J0TQ83
    Related
    ENSXLAP00005106925.1, ENSXLAT00005109037.1

  5. XM_041578151.1 → XP_041434085.1  myb-related protein B isoform X5

    UniProtKB/TrEMBL
    A0A8J1LZD0, Q6NRE6
    Related
    ENSXLAP00005106875.1, ENSXLAT00005108987.1
    Conserved Domains (2) summary
    PLN03091
    Location:77 → 254
    PLN03091; hypothetical protein; Provisional
    pfam13921
    Location:30 → 90
    Myb_DNA-bind_6; Myb-like DNA-binding domain

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001088381.1: Suppressed sequence

    Description
    NM_001088381.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P52551.2 GenPept UniProtKB/Swiss-Prot:P52551

Gene LinkOut

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