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tcea2.S transcription elongation factor A2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398066, updated on 4-Nov-2024

Summary

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Official Symbol
tcea2.S
Official Full Name
transcription elongation factor A2 S homeolog
Primary source
Xenbase:XB-GENE-6252033
Locus tag
XELAEV_18046335mg
See related
EnsemblRapid:ENSXLAG00005024091 AllianceGenome:Xenbase:XB-GENE-6252033
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
tcea3; tfiis; tcea3-a; tcea3-b; tfIIs.h
Summary
Predicted to enable DNA binding activity; translation elongation factor activity; and zinc ion binding activity. Predicted to act upstream of or within transcription elongation by RNA polymerase II and translational elongation. Predicted to be located in nucleus. [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See tcea2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (17260681..17266389, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (16571330..16577011, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A protein 2-like Neighboring gene protein kinase C delta type Neighboring gene SRY-box 18 S homeolog Neighboring gene Rh associated glycoprotein like S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcript cleavage in an RNA polymerase I elongation complex. Evidence for a dissociable activity similar to but distinct from TFIIS. Labhart P. J Biol Chem, 1997 Apr 4. PMID 9083031
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
  
enables translation elongation factor activity IEA
Inferred from Electronic Annotation
more info
  
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within transcription elongation by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within translational elongation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
transcription elongation factor A2 S homeolog
Names
transcription elongation factor A (SII), 2 S homeolog
transcription elongation factor type xTFIIS.l

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088343.1 → NP_001081812.1  transcription elongation factor A2 S homeolog

    See identical proteins and their annotated locations for NP_001081812.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068738
    UniProtKB/TrEMBL
    Q91692
    Related
    ENSXLAP00005071321.1, ENSXLAT00005072868.1
    Conserved Domains (4) summary
    cd00183
    Location:5 → 81
    TFIIS_I; N-terminal domain (domain I) of transcription elongation factor S-II (TFIIS); similar to a domain found in elongin A and CRSP70; likely to be involved in transcription; domain I from TFIIS interacts with RNA polymerase II holoenzyme
    cd13749
    Location:245 → 291
    Zn-ribbon_TFIIS; domain III/zinc ribbon domain of Transcription Factor IIS
    TIGR01385
    Location:5 → 292
    TFSII; transcription elongation factor S-II
    pfam07500
    Location:129 → 236
    TFIIS_M; Transcription factor S-II (TFIIS), central domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    17260681..17266389 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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Research Materials