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arr3.L arrestin 3, retinal (X-arrestin) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 398046, updated on 4-Nov-2024

Summary

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Official Symbol
arr3.L
Official Full Name
arrestin 3, retinal (X-arrestin) L homeolog
Primary source
Xenbase:XB-GENE-966163
Locus tag
XELAEV_18038631mg
See related
EnsemblRapid:ENSXLAG00005013398 AllianceGenome:Xenbase:XB-GENE-966163
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
arr3
Summary
Predicted to enable G protein-coupled receptor binding activity. Predicted to act upstream of or within G protein-coupled receptor internalization; signal transduction; and visual perception. Is expressed in visual system. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See arr3.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
17
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (34391623..34410228)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (21300771..21319328)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100127316 Neighboring gene RAB41, member RAS oncogene family L homeolog Neighboring gene inositol polyphosphate phosphatase-like 1B L homeolog Neighboring gene pyrimidinergic receptor P2Y, G-protein coupled, 4 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The arrestin superfamily: cone arrestins are a fourth family. Craft CM, et al. FEBS Lett, 1995 Apr 3. PMID 7720881
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables G protein-coupled receptor binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within G protein-coupled receptor internalization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within signal transduction IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within visual perception IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
arrestin-C
Names
cone arrestin

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088311.1 → NP_001081780.1  arrestin-C

    See identical proteins and their annotated locations for NP_001081780.1

    Status: PROVISIONAL

    Source sequence(s)
    L40463
    UniProtKB/Swiss-Prot
    P51483
    UniProtKB/TrEMBL
    Q52KS9
    Related
    ENSXLAP00005039575.1, ENSXLAT00005040497.1
    Conserved Domains (2) summary
    smart01017
    Location:192 → 355
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    cl22903
    Location:17 → 173
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    34391623..34410228
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041571933.1 → XP_041427867.1  arrestin-C isoform X1

    UniProtKB/TrEMBL
    A0A1L8F6X4, A0A974H7M0, Q52KS9
    Related
    ENSXLAP00005039557.1, ENSXLAT00005040476.1
    Conserved Domains (2) summary
    smart01017
    Location:192 → 355
    Arrestin_C; Arrestin (or S-antigen), C-terminal domain
    cl22903
    Location:19 → 173
    Arrestin_N; Arrestin (or S-antigen), N-terminal domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P51483.1 GenPept UniProtKB/Swiss-Prot:P51483

Gene LinkOut

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