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orc4.L origin recognition complex subunit 4 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397923, updated on 18-Sep-2024

Summary

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Official Symbol
orc4.L
Official Full Name
origin recognition complex subunit 4 L homeolog
Primary source
Xenbase:XB-GENE-1012486
Locus tag
XELAEV_18044554mg
See related
EnsemblRapid:ENSXLAG00005030769
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
orc4; orc4l
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Genomic context

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See orc4.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
14
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (67546891..67569836, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (57027795..57050973, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121398243 Neighboring gene activin A receptor type 2A L homeolog Neighboring gene uncharacterized LOC108701319 Neighboring gene methyl-CpG binding domain protein 5 L homeolog Neighboring gene enhancer of polycomb homolog 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The Orc4p and Orc5p subunits of the Xenopus and human origin recognition complex are related to Orc1p and Cdc6p. Tugal T, et al. J Biol Chem, 1998 Dec 4. PMID 9829972
  2. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Clone Names

  • MGC130913

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA binding IEA
Inferred from Electronic Annotation
more info
  
enables DNA replication origin binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within DNA replication IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within DNA replication initiation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of nuclear origin of replication recognition complex IEA
Inferred from Electronic Annotation
more info
  
part_of nuclear origin of replication recognition complex ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of origin recognition complex IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
origin recognition complex subunit 4
Names
origin recognition complex, subunit 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001088092.1 → NP_001081561.1  origin recognition complex subunit 4

    See identical proteins and their annotated locations for NP_001081561.1

    Status: PROVISIONAL

    Source sequence(s)
    BC106363
    UniProtKB/Swiss-Prot
    O93479
    UniProtKB/TrEMBL
    Q3B8I2
    Related
    ENSXLAP00005092160.1, ENSXLAT00005093844.1
    Conserved Domains (3) summary
    smart00382
    Location:62 → 216
    AAA; ATPases associated with a variety of cellular activities
    pfam13191
    Location:34 → 188
    AAA_16; AAA ATPase domain
    pfam14629
    Location:226 → 403
    ORC4_C; Origin recognition complex (ORC) subunit 4 C-terminus

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    67546891..67569836 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O93479.1 GenPept UniProtKB/Swiss-Prot:O93479

Gene LinkOut

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