ssbp1.L single-stranded DNA binding protein 1, mitochondrial L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ssbp1.L
Official Full Name: single-stranded DNA binding protein 1, mitochondrial L homeolog
Primary source: Xenbase:XB-GENE-6252172
Locus tag: XELAEV_18002464mg
See related: EnsemblRapid:ENSXLAG00005010277 AllianceGenome:Xenbase:XB-GENE-6252172
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ssbp; XL 31; mtssb; ssbp1; mt-ssb; mtssb1; soss-b1; ssbp1-a; ssbp1-b
Summary: Predicted to enable chromatin binding activity and single-stranded DNA binding activity. Predicted to act upstream of or within positive regulation of mitochondrial DNA replication and protein homotetramerization. Predicted to be located in mitochondrial nucleoid. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human SSBP1 (single stranded DNA binding protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

Location:: chromosome: 3L

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	3L	NC_054375.1 (5615545..5625378, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	Unplaced Scaffold	NW_016694822.1 (321293..330903)

Chromosome 3L - NC_054375.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info
enables single-stranded DNA binding	IEA Inferred from Electronic Annotation more info
enables single-stranded DNA binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitochondrial DNA replication	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of helicase activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of mitochondrial DNA replication	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within protein homotetramerization	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
located_in mitochondrial nucleoid	IEA Inferred from Electronic Annotation more info
located_in mitochondrial nucleoid	ISS Inferred from Sequence or Structural Similarity more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	ISS Inferred from Sequence or Structural Similarity more info

General protein information

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Preferred Names: single-stranded DNA-binding protein 1-A, mitochondrial

Names: mitochondrial DNA specific single-stranded DNA binding protein (mt-SSB); mtSSB-1; mtSSBs; single-stranded DNA-binding protein 1, mitochondrial; single-stranded DNA-binding protein S, mitochondrial; xl-mtssb; xlSSB1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001101771.1 → NP_001095241.1 single-stranded DNA-binding protein 1-A, mitochondrial precursor

See identical proteins and their annotated locations for NP_001095241.1

Status: PROVISIONAL

Source sequence(s)

X59285

UniProtKB/Swiss-Prot

P09380, Q66GV9

UniProtKB/TrEMBL

B7ZPW2

Related

ENSXLAP00005030371.1, ENSXLAT00005031128.1

Conserved Domains (2) summary

COG0629
Location:27 → 140

Ssb; Single-stranded DNA-binding protein [Replication, recombination and repair]

cl09930
Location:25 → 140

RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.