ccna1.S cyclin A1 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ccna1.S
Official Full Name: cyclin A1 S homeolog
Primary source: Xenbase:XB-GENE-17338602
Locus tag: XELAEV_18016158mg
See related: EnsemblRapid:ENSXLAG00005021269
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: ccna1; Cyclin-A1
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Genomic context

Location:: chromosome: 2S

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	2S	NC_054374.1 (143829831..143838570, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	2S	NC_030727.1 (134816795..134825614, complement)

Chromosome 2S - NC_054374.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

evidence that cyclin A1-associated activity is a mediator of apoptosis and that cyclin A1/Cdk2 is sufficient to induce apoptosis
Title: Cyclin A1/Cdk2 is sufficient but not required for the induction of apoptosis in early Xenopus laevis embryos.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables cyclin-dependent protein serine/threonine kinase regulator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within mitotic cell cycle phase transition	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of cyclin-dependent protein serine/threonine kinase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of cyclin A2-CDK2 complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: cyclin-A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001088046.1 → NP_001081515.1 cyclin-A1

See identical proteins and their annotated locations for NP_001081515.1

Status: PROVISIONAL

Source sequence(s)

BC074115

UniProtKB/TrEMBL

A0A974HX35, Q6GME9

Related

ENSXLAP00005062373.1, ENSXLAT00005063826.1

Conserved Domains (3) summary

pfam00134
Location:167 → 293

Cyclin_N; Cyclin, N-terminal domain

pfam02984
Location:295 → 412

Cyclin_C; Cyclin, C-terminal domain

pfam16500
Location:26 → 143

Cyclin_N2; N-terminal region of cyclin_N

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054374.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

143829831..143838570 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)