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efna1.S ephrin-A1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397809, updated on 4-Nov-2024

Summary

Official Symbol
efna1.S
Official Full Name
ephrin-A1 S homeolog
Primary source
Xenbase:XB-GENE-6252357
Locus tag
XELAEV_18043012mg
See related
EnsemblRapid:ENSXLAG00005006765 AllianceGenome:Xenbase:XB-GENE-6252357
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
b61; elf; efl1; ecklg; efna1; epgl1; epha1; eplg1; lerk1; xelfa; efna1a; elfa-a; efna1-a; efna1-b; efna1.L; tnfaip4; xelf-a'; ephrinA1; Xefrin-A1
Summary
Predicted to enable ephrin receptor binding activity. Predicted to act upstream of or within ephrin receptor signaling pathway; negative regulation of dendritic spine morphogenesis; and regulation of peptidyl-tyrosine phosphorylation. Predicted to be located in plasma membrane and side of membrane. Is expressed in dermal system and ectoderm. Orthologous to human EFNA1 (ephrin A1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

See efna1.S in Genome Data Viewer
Location:
chromosome: 8S
Exon count:
5
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8S NC_054386.1 (103337643..103344068)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8S NC_030739.1 (98358619..98365046)

Chromosome 8S - NC_054386.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121397608 Neighboring gene ephrin A3 L homeolog Neighboring gene tripartite motif containing 46 S homeolog Neighboring gene mucin 1, cell surface associated S homeolog

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables ephrin receptor binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within axon guidance IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ephrin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
acts_upstream_of_or_within ephrin receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within negative regulation of dendritic spine morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
acts_upstream_of_or_within regulation of peptidyl-tyrosine phosphorylation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 
located_in side of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
ephrin-A1
Names
EPH-related receptor tyrosine kinase ligand 1
LERK-1
XELF-a
eph ligand family-a
ephrin-A1 L homeolog
ephrin-A1a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087921.1NP_001081390.1  ephrin-A1 precursor

    See identical proteins and their annotated locations for NP_001081390.1

    Status: PROVISIONAL

    Source sequence(s)
    U31205
    UniProtKB/Swiss-Prot
    P52794
    Conserved Domains (1) summary
    cd10425
    Location:29158
    Ephrin-A_Ectodomain; Ectodomain of Ephrin A

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054386.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    103337643..103344068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018231893.2XP_018087382.1  ephrin-A1 isoform X1

    UniProtKB/Swiss-Prot
    P52794
    UniProtKB/TrEMBL
    A0A1L8F582, A0A974C5A5
    Related
    ENSXLAP00005019912.1, ENSXLAT00005020312.1
  2. XM_018231894.2XP_018087383.1  ephrin-A1 isoform X2

    UniProtKB/Swiss-Prot
    P52794
    UniProtKB/TrEMBL
    A0A8J0TMD7
    Related
    ENSXLAP00005019923.1, ENSXLAT00005020328.1