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rcc1.L regulator of chromosome condensation 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 397722, updated on 4-Nov-2024

Summary

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Official Symbol
rcc1.L
Official Full Name
regulator of chromosome condensation 1 L homeolog
Primary source
Xenbase:XB-GENE-6252622
Locus tag
XELAEV_18012073mg
See related
EnsemblRapid:ENSXLAG00005031966 AllianceGenome:Xenbase:XB-GENE-6252622
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
chc1; rcc1; xrcc1; RanGEF; chc1-a; rcc1-a; rcc1-b
Summary
Predicted to enable guanyl-nucleotide exchange factor activity. Predicted to act upstream of or within cell division. Predicted to be located in chromosome; cytoplasm; and nucleus. Orthologous to human RCC1 (regulator of chromosome condensation 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See rcc1.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
11
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (60095758..60110655)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (57574775..57589652)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene Scm polycomb group protein homolog 1 L homeolog Neighboring gene palmitoyltransferase ZDHHC20-like Neighboring gene CTP synthase 1 L homeolog Neighboring gene opioid receptor delta 1 L homeolog Neighboring gene ctranscription elongation factor A (SII), 3 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Cloning of Xenopus RCC1 cDNA, a homolog of the human RCC1 gene: complementation of tsBN2 mutation and identification of the product. Nishitani H, et al. J Biochem, 1990 Feb. PMID 2361953
  2. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nishiyama A, et al. Nat Commun, 2020 Mar 6. PMID 32144273, Free PMC Article
  3. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
regulator of chromosome condensation
Names
chromosome condensation 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087760.1 → NP_001081229.1  regulator of chromosome condensation

    See identical proteins and their annotated locations for NP_001081229.1

    Status: PROVISIONAL

    Source sequence(s)
    D00679
    UniProtKB/Swiss-Prot
    P25183
    UniProtKB/TrEMBL
    Q6IRM1
    Conserved Domains (2) summary
    pfam00415
    Location:368 → 419
    RCC1; Regulator of chromosome condensation (RCC1) repeat
    pfam13540
    Location:180 → 209
    RCC1_2; Regulator of chromosome condensation (RCC1) repeat

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    60095758..60110655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_018244855.2 → XP_018100344.1  regulator of chromosome condensation isoform X1

    UniProtKB/TrEMBL
    A0A974DMH2, Q08B75, Q6IRM1
    Related
    ENSXLAP00005095850.1, ENSXLAT00005097616.1

  2. XM_018244856.2 → XP_018100345.1  regulator of chromosome condensation isoform X1

    UniProtKB/TrEMBL
    A0A974DMH2, Q08B75, Q6IRM1
    Related
    ENSXLAP00005095764.1, ENSXLAT00005097521.1
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P25183.1 GenPept UniProtKB/Swiss-Prot:P25183

Gene LinkOut

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