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STAT5A signal transducer and activator of transcription 5A [ Sus scrofa (pig) ]

Gene ID: 397550, updated on 12-Oct-2024

Summary

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Official Symbol
STAT5Aprovided by VGNC
Official Full Name
signal transducer and activator of transcription 5Aprovided by VGNC
Primary source
VGNC:VGNC:99087
See related
Ensembl:ENSSSCG00000017402
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression
Ubiquitous expression in spleen (RPKM 24.8), subcutaneous adipose (RPKM 24.0) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See STAT5A in Genome Data Viewer
Location:
chromosome: 12
Exon count:
20
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (20474221..20498785, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (24563982..24581115)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110256002 Neighboring gene caveolae associated protein 1 Neighboring gene signal transducer and activator of transcription 3 Neighboring gene signal transducer and activator of transcription 5B Neighboring gene GH3 domain containing Neighboring gene hypocretin neuropeptide precursor Neighboring gene RAB5C, member RAS oncogene family

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Assignment of Signal Transducer and Activator of Transcription 5A (STAT5A) gene to porcine chromosome 12p13-->p11 by radiation hybrid panel mapping. Sardina MT, et al. Cytogenet Genome Res, 2006. PMID 16484801
  2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Mapped to chromosome 12 by radiation hybrid mapping.
    Title: Assignment of Signal Transducer and Activator of Transcription 5A (STAT5A) gene to porcine chromosome 12p13-->p11 by radiation hybrid panel mapping.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 5A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214290.1 → NP_999455.1  signal transducer and activator of transcription 5A

    See identical proteins and their annotated locations for NP_999455.1

    Status: PROVISIONAL

    Source sequence(s)
    AF135122
    UniProtKB/Swiss-Prot
    Q9TUZ1
    UniProtKB/TrEMBL
    A0A8D1JES4, A0A8D2BNV0, E0AD96
    Related
    ENSSSCP00000078841.1, ENSSSCT00000105143.1
    Conserved Domains (4) summary
    pfam01017
    Location:141 → 330
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:332 → 582
    STAT_bind; STAT protein, DNA binding domain
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 712
    SH2; Src homology 2 (SH2) domain

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    20474221..20498785 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021066247.1 → XP_020921906.1  signal transducer and activator of transcription 5A isoform X1

    UniProtKB/TrEMBL
    A0A0A0MY60, A0A8D1JES4, E0AD96
    Related
    ENSSSCP00000018442.3, ENSSSCT00000018947.4
    Conserved Domains (4) summary
    pfam01017
    Location:141 → 330
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:332 → 582
    STAT_bind; STAT protein, DNA binding domain
    pfam02865
    Location:2 → 124
    STAT_int; STAT protein, protein interaction domain
    cl15255
    Location:573 → 712
    SH2; Src homology 2 (SH2) domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9TUZ1.1 GenPept UniProtKB/Swiss-Prot:Q9TUZ1

Gene LinkOut

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Molecular Biology Databases
Research Materials