CEBPB CCAAT enhancer binding protein beta [Sus scrofa (pig)] - Gene

Summary

Official Symbol: CEBPBprovided by VGNC
Official Full Name: CCAAT enhancer binding protein betaprovided by VGNC
Primary source: VGNC:VGNC:95883
See related: Ensembl:ENSSSCG00000034207
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	17	NC_010459.5 (51722633..51723673)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	17	NC_010459.4 (58041640..58042680)

Chromosome 17 - NC_010459.5 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The C/EBPbeta-Dependent Induction of TFDP2 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Proliferation.
Title: The C/EBPβ-Dependent Induction of TFDP2 Facilitates Porcine Reproductive and Respiratory Syndrome Virus Proliferation.
C/EBP-beta plays a vital role in regulating GPR120 transcription.
Title: Transcription factor C/EBPβ promotes the transcription of the porcine GPR120 gene.
The expression of porcine Prdx6 gene is up-regulated by C/EBPbeta and CREB.
Title: The Expression of Porcine Prdx6 Gene Is Up-Regulated by C/EBPβ and CREB.
Results show that expression changes of IGF1 genes were associated with C/EBP b expression during embryonic and postnatal development in porcine liver.
Title: CCAAT-enhancer binding protein (C/EBP) β regulates insulin-like growth factor (IGF) 1 expression in porcine liver during prenatal and postnatal development.
FoxO1 and C/EBPb regulate preadipocyte adipogenesis possibly through C/EBPb-> FoxO1-> C/EBPb feedback regulatory loop and FoxO1-C/EBPb protein complex.
Title: Knockdown of both FoxO1 and C/EBPβ promotes adipogenesis in porcine preadipocytes through feedback regulation.
the pig GPD1 gene is regulated negatively by C/EBP beta in cultured kidney cells
Title: CCAAT/enhancer binding protein-beta negatively regulates the expression of glycerol-3-phosphate dehydrogenase 1 in pig PK-15 cells.
The differential expression of specific CEBPA/B isoforms observed in maturing follicles and CL may contribute to changes in follicular cell differentiation and increasing steroidogenic capacity.
Title: Expression of CCAAT/enhancer binding proteins alpha and beta in the porcine ovary and regulation in primary cultures of granulosa cells.
GATA-4 and C/EBPbeta are both required for FSH +/- IGF-I stimulation of the porcine steroidogenic acute regulatory protein gene promoter in homologous granulosa cell cultures.
Title: Concerted regulation of the porcine steroidogenic acute regulatory protein gene promoter activity by follicle-stimulating hormone and insulin-like growth factor I in granulosa cells involves GATA-4 and CCAAT/enhancer binding protein beta.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in DNA-templated transcription	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: CCAAT/enhancer-binding protein beta

Names: CCAAT/enhancer binding protein (C/EBP), beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001199889.2 → NP_001186818.1 CCAAT/enhancer-binding protein beta

See identical proteins and their annotated locations for NP_001186818.1

Status: VALIDATED

Source sequence(s)

AEMK02000106

UniProtKB/TrEMBL

A0A8D0SG50, E5Q8C6

Related

ENSSSCP00000045801.1, ENSSSCT00000037850.2

Conserved Domains (1) summary

cd14712
Location:265 → 335

bZIP_CEBPB; Basic leucine zipper (bZIP) domain of CCAAT/enhancer-binding protein beta (CEBPB): a DNA-binding and dimerization domain