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IGF2R insulin like growth factor 2 receptor [ Sus scrofa (pig) ]

Gene ID: 397214, updated on 17-Aug-2024

Summary

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Official Symbol
IGF2Rprovided by VGNC
Official Full Name
insulin like growth factor 2 receptorprovided by VGNC
Primary source
VGNC:VGNC:89057
See related
Ensembl:ENSSSCG00000004044
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
M6P/IGF2R
Expression
Ubiquitous expression in kidney (RPKM 29.8), lung (RPKM 21.0) and 8 other tissues See more
Orthologs
human mouse all
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Genomic context

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See IGF2R in Genome Data Viewer
Location:
chromosome: 1
Exon count:
48
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 1 NC_010443.5 (7369485..7472480, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 1 NC_010443.4 (9168321..9271328, complement)

Chromosome 1 - NC_010443.5Genomic Context describing neighboring genes Neighboring gene solute carrier family 22 member 2 Neighboring gene uncharacterized LOC102165795 Neighboring gene uncharacterized LOC110259889 Neighboring gene solute carrier family 22 member 1 Neighboring gene uncharacterized LOC102166961 Neighboring gene MAS1 proto-oncogene, G protein-coupled receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Biallelic transcription of the porcine IGF2R gene. Braunschweig MH. Gene, 2012 Jun 1. PMID 22503898
  2. Marsupials and Eutherians reunited: genetic evidence for the Theria hypothesis of mammalian evolution. Killian JK, et al. Mamm Genome, 2001 Jul. PMID 11420613
  3. Identification of SNPs and INDELS in swine transcribed sequences using short oligonucleotide microarrays. Bischoff SR, et al. BMC Genomics, 2008 May 29. PMID 18510738, Free PMC Article
  4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

See all (7) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables D-mannose binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin-like growth factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in lysosomal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in late endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cation-independent mannose-6-phosphate receptor
Names
insulin growth factor 2 receptor
insulin-like growth factor II receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001244473.1 → NP_001231402.1  cation-independent mannose-6-phosphate receptor precursor

    See identical proteins and their annotated locations for NP_001231402.1

    Status: PROVISIONAL

    Source sequence(s)
    JF894230
    UniProtKB/TrEMBL
    A0A8D0X5J5, F8UQW4
    Related
    ENSSSCP00000004370.3, ENSSSCT00000004472.4
    Conserved Domains (2) summary
    smart00059
    Location:1898 → 1943
    FN2; Fibronectin type 2 domain
    pfam00878
    Location:1323 → 1463
    CIMR; Cation-independent mannose-6-phosphate receptor repeat

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010443.5 Reference Sscrofa11.1 Primary Assembly

    Range
    7369485..7472480 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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