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UPK2 uroplakin 2 [ Sus scrofa (pig) ]

Gene ID: 397075, updated on 17-Aug-2024

Summary

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Official Symbol
UPK2provided by VGNC
Official Full Name
uroplakin 2provided by VGNC
Primary source
VGNC:VGNC:94723
See related
Ensembl:ENSSSCG00000015100
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
UP2; UPII
Expression
Biased expression in kidney (RPKM 2.6), lung (RPKM 0.7) and 2 other tissues See more
Orthologs
human mouse all
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Genomic context

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See UPK2 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 9 NC_010451.4 (46200465..46202754)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 9 NC_010451.3 (51233373..51237823)

Chromosome 9 - NC_010451.4Genomic Context describing neighboring genes Neighboring gene C-X-C motif chemokine receptor 5 Neighboring gene BCL9 like Neighboring gene uncharacterized LOC110255441 Neighboring gene forkhead box R1 Neighboring gene myeloid leukemia factor 2 pseudogene Neighboring gene centrosomal AT-AC splicing factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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Related articles in PubMed

  1. Cloning and molecular dissection of the 8.8 kb pig uroplakin II promoter using transgenic mice and RT4 cells. Kwon DN, et al. J Cell Biochem, 2006 Oct 1. PMID 16619260
  2. Characterization of a putative cis-regulatory element that controls transcriptional activity of the pig uroplakin II gene promoter. Kwon DN, et al. Biochem Biophys Res Commun, 2011 Jul 1. PMID 21658368
  3. Cloning, sequencing, and expression analysis of the porcine uroplakin II gene. Kwon DN, et al. Biochem Biophys Res Commun, 2002 May 3. PMID 12054551
  4. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
  5. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. HNF4 positively regulates pUPII gene promoter activity.
    Title: Characterization of a putative cis-regulatory element that controls transcriptional activity of the pig uroplakin II gene promoter.
  2. all the major trans-regulatory elements required for bladder- and urethra-specific transcription are located in the 8.8 kb promoter upstream region
    Title: Cloning and molecular dissection of the 8.8 kb pig uroplakin II promoter using transgenic mice and RT4 cells.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in epithelial cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
uroplakin-2
Names
uroplakin II

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_214012.1 → NP_999177.1  uroplakin-2 precursor

    See identical proteins and their annotated locations for NP_999177.1

    Status: PROVISIONAL

    Source sequence(s)
    AF164141
    UniProtKB/TrEMBL
    A0A8D1SX19, A0A8D2A9I1, F1SAJ2
    Related
    ENSSSCP00000016023.4, ENSSSCT00000016466.5
    Conserved Domains (1) summary
    cl06408
    Location:24 → 184
    UP_III_II; Uroplakin IIIb, IIIa and II

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010451.4 Reference Sscrofa11.1 Primary Assembly

    Range
    46200465..46202754
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021102209.1 → XP_020957868.1  uroplakin-2 isoform X1

    UniProtKB/TrEMBL
    A0A8D1MQD5, A0A8D1SX19, A0A8D2A9I1, F1SAJ2
    Conserved Domains (1) summary
    cl06408
    Location:25 → 185
    UP_III_II; Uroplakin IIIb, IIIa and II
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q95L04.3 GenPept UniProtKB/Swiss-Prot:Q95L04

Gene LinkOut

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