HEXB hexosaminidase subunit beta [Sus scrofa (pig)] - Gene

Summary

Official Symbol: HEXBprovided by VGNC
Official Full Name: hexosaminidase subunit betaprovided by VGNC
Primary source: VGNC:VGNC:88861
See related: Ensembl:ENSSSCG00000014073
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in kidney (RPKM 118.9), lung (RPKM 76.8) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 2

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	2	NC_010444.4 (83745263..83784762)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	2	NC_010444.3 (85331866..85371568)

Chromosome 2 - NC_010444.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables beta-N-acetylhexosaminidase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in ganglioside catabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in glycosaminoglycan metabolic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: beta-hexosaminidase subunit beta

Names: 65 kDa epididymal boar protein; N-acetyl-beta-glucosaminidase subunit beta; beta-N-acetylhexosaminidase subunit beta; hexosaminidase subunit B

NP_999086.2

EC 3.2.1.52

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_213921.2 → NP_999086.2 beta-hexosaminidase subunit beta precursor

Status: VALIDATED

Source sequence(s)

AB529531, AK233473, BP144371

UniProtKB/TrEMBL

A0A286ZKQ1, A0A4X1SN32, A0A4X1SPP3, A0A8D0QWQ2, D0G6X8, F1S2J8

Related

ENSSSCP00000014965.2, ENSSSCT00000015373.4

Conserved Domains (2) summary

cd06562
Location:181 → 521

GH20_HexA_HexB-like; Beta-N-acetylhexosaminidases catalyze the removal of beta-1,4-linked N-acetyl-D-hexosamine residues from the non-reducing ends of N-acetyl-beta-D-hexosaminides including N-acetylglucosides and N-acetylgalactosides. The hexA and hexB genes encode the ...

pfam14845
Location:39 → 159

Glycohydro_20b2; beta-acetyl hexosaminidase like