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AURKB aurora kinase B [ Sus scrofa (pig) ]

Gene ID: 396955, updated on 17-Aug-2024

Summary

Official Symbol
AURKBprovided by VGNC
Official Full Name
aurora kinase Bprovided by VGNC
Primary source
VGNC:VGNC:85698
See related
Ensembl:ENSSSCG00000028924
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Also known as
AIM-1; ARK-2; STK-1; STK12
Expression
Ubiquitous expression in spleen (RPKM 4.0), lung (RPKM 3.6) and 8 other tissues See more
Orthologs
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Genomic context

See AURKB in Genome Data Viewer
Location:
chromosome: 12
Exon count:
17
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 12 NC_010454.4 (53410833..53426165, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 12 NC_010454.3 (55886065..55894911, complement)

Chromosome 12 - NC_010454.4Genomic Context describing neighboring genes Neighboring gene BLOC-1 related complex subunit 6 Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene transfer RNA isoleucine (anticodon AAU) Neighboring gene transfer RNA tryptophan (anticodon CCA) Neighboring gene transfer RNA glycine (anticodon UCC) Neighboring gene transfer RNA aspartic acid (anticodon GUC) Neighboring gene transfer RNA proline (anticodon CGG) Neighboring gene transfer RNA threonine (anticodon AGU) Neighboring gene transfer RNA serine (anticodon AGA)

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in mitotic spindle organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cytokinesis IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of chromosome passenger complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in spindle microtubule IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in spindle midzone IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in spindle pole centrosome IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
aurora kinase B
Names
Serine/threonine-protein kinase 12
aurora 1
aurora- and IPL1-like midbody-associated protein 1
aurora-related kinase 2
aurora/IPL1-related kinase 2
serine/threonine kinase 12
serine/threonine-protein kinase 5
serine/threonine-protein kinase aurora-B
NP_999084.2
XP_013845502.2
XP_013845504.2
XP_020921847.1
XP_020921848.1
XP_020921849.1
XP_020921850.1
XP_020921851.1
XP_020921852.1
XP_020921854.1
XP_020921855.1
XP_020921856.1
XP_020921857.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_213919.2NP_999084.2  aurora kinase B

    Status: VALIDATED

    Source sequence(s)
    AK234554, AK398886
    UniProtKB/Swiss-Prot
    Q7YRC7, Q9N0X0
    UniProtKB/TrEMBL
    A0A4X1VAK4
    Related
    ENSSSCP00000022968.3, ENSSSCT00000025604.4
    Conserved Domains (1) summary
    cd14117
    Location:70339
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010454.4 Reference Sscrofa11.1 Primary Assembly

    Range
    53410833..53426165 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021066189.1XP_020921848.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  2. XM_013990050.2XP_013845504.2  aurora kinase B isoform X2

    Conserved Domains (1) summary
    cd14117
    Location:145414
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  3. XM_021066188.1XP_020921847.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  4. XM_021066193.1XP_020921852.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  5. XM_021066195.1XP_020921854.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  6. XM_021066190.1XP_020921849.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Related
    ENSSSCP00000061822.1, ENSSSCT00000090078.2
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  7. XM_021066191.1XP_020921850.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  8. XM_021066192.1XP_020921851.1  aurora kinase B isoform X1

    UniProtKB/TrEMBL
    A0A5G2QDV6
    Conserved Domains (1) summary
    cd14117
    Location:169438
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  9. XM_021066198.1XP_020921857.1  aurora kinase B isoform X5

    UniProtKB/TrEMBL
    A0A4X1V985
    Conserved Domains (1) summary
    cd14117
    Location:121390
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  10. XM_021066197.1XP_020921856.1  aurora kinase B isoform X4

    Conserved Domains (1) summary
    cl21453
    Location:21187
    PKc_like; Protein Kinases, catalytic domain
  11. XM_021066196.1XP_020921855.1  aurora kinase B isoform X3

    UniProtKB/TrEMBL
    A0A8D1W4X7
    Conserved Domains (1) summary
    cd14117
    Location:29298
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins
  12. XM_013990048.2XP_013845502.2  aurora kinase B isoform X3

    UniProtKB/TrEMBL
    A0A8D1W4X7
    Conserved Domains (1) summary
    cd14117
    Location:29298
    STKc_Aurora-B_like; Catalytic domain of the Serine/Threonine kinase, Aurora-B kinase and similar proteins