CD8B CD8 subunit beta [Sus scrofa (pig)] - Gene

Summary

Gene symbol: CD8B
Gene description: CD8 subunit beta
See related: Ensembl:ENSSSCG00000008213
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Sus scrofa
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Expression: Broad expression in spleen (RPKM 6.4), lung (RPKM 2.9) and 6 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 3

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
106	current	Sscrofa11.1 (GCF_000003025.6)	3	NC_010445.4 (57968358..57986450)
105	previous assembly	Sscrofa10.2 (GCF_000003025.5)	3	NC_010445.3 (60577367..60679569)

Chromosome 3 - NC_010445.4 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
BioProject: PRJNA311523
Publication: PMID 27646534
Analysis date: Thu Dec 14 17:10:49 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

FABP1 (e-PCR)
- UniSTS:253975

RH70351 (e-PCR)
- UniSTS:70961

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables MHC class I protein binding	IEA Inferred from Electronic Annotation more info	PubMed
enables coreceptor activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of immune response	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cell surface	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: T-cell surface glycoprotein CD8 beta chain

Names: CD8 antigen beta polypeptide; CD8b molecule

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001348770.1 → NP_001335699.1 T-cell surface glycoprotein CD8 beta chain precursor

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the protein-coding transcript.

Source sequence(s)

AK239664, CU856068

UniProtKB/TrEMBL

A0A8D0ISD0, Q764N0

Related

ENSSSCP00000008768.6, ENSSSCT00000008994.6

Conserved Domains (1) summary

cd07700
Location:29 → 133

IgV_CD8_beta; Immunoglobulin (Ig) like domain of CD8 beta chain

RNA

NR_145981.2 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses an alternate splice site in an internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).

Source sequence(s)

AEMK02000020, AK239664