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GPX3 glutathione peroxidase 3 [ Sus scrofa (pig) ]

Gene ID: 396598, updated on 17-Aug-2024

Summary

Official Symbol
GPX3provided by VGNC
Official Full Name
glutathione peroxidase 3provided by VGNC
Primary source
VGNC:VGNC:98026
See related
Ensembl:ENSSSCG00000036438
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Sus scrofa
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
Annotation information
Annotation category: partial on reference assembly
Expression
Biased expression in kidney (RPKM 6951.3), mixtures (RPKM 1249.7) and 1 other tissue See more
Orthologs
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Genomic context

See GPX3 in Genome Data Viewer
Location:
chromosome: 16
Exon count:
5
Annotation release Status Assembly Chr Location
106 current Sscrofa11.1 (GCF_000003025.6) 16 NC_010458.4 (71980467..71989011, complement)
105 previous assembly Sscrofa10.2 (GCF_000003025.5) 16 NC_010458.3 (78282309..78290916)

Chromosome 16 - NC_010458.4Genomic Context describing neighboring genes Neighboring gene annexin A6 Neighboring gene TNFAIP3 interacting protein 1 Neighboring gene uncharacterized LOC106506567 Neighboring gene membrane associated ring-CH-type finger 6

Genomic regions, transcripts, and products

Expression

  • Project title: Transcriptome data used for gene annotation Transcriptome data used for gene annotation
  • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
  • BioProject: PRJNA311523
  • Publication: PMID 27646534
  • Analysis date: Thu Dec 14 17:10:49 2017

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables glutathione peroxidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables selenium binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in hydrogen peroxide catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
glutathione peroxidase 3
Names
glutathione peroxidase 3 (plasma)
NP_001108627.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001115155.1NP_001108627.1  glutathione peroxidase 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AK236369, DV936676
    UniProtKB/TrEMBL
    A0A8D1IFL0
    Related
    ENSSSCP00000043711.2, ENSSSCT00000046829.3
    Conserved Domains (1) summary
    cd00340
    Location:39211
    GSH_Peroxidase; Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per ...

RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Sscrofa11.1 Primary Assembly

Genomic

  1. NC_010458.4 Reference Sscrofa11.1 Primary Assembly

    Range
    71980467..71989011 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)