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DBN1 drebrin 1 [ Gallus gallus (chicken) ]

Gene ID: 396496, updated on 10-Oct-2024

Summary

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Symbol
DBN1provided by CGNC
Full Name
drebrin 1provided by CGNC
Primary source
CGNC:49836
See related
Ensembl:ENSGALG00010008906
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See DBN1 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (9757143..9769410, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (9762921..9775200, complement)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene alpha-2B adrenergic receptor-like 2 Neighboring gene G protein-coupled receptor kinase 6 Neighboring gene proline rich 7, synaptic Neighboring gene PDZ and LIM domain 7 Neighboring gene docking protein 3 Neighboring gene DEAD-box helicase 41 Neighboring gene family with sequence similarity 193 member B Neighboring gene zinc finger FYVE-type containing 28B

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Molecular Cloning of Drebrin: Progress and Perspectives. Kojima N. Adv Exp Med Biol, 2017. PMID 28865012
  2. Molecular cloning of a developmentally regulated brain protein, chicken drebrin A and its expression by alternative splicing of the drebrin gene. Kojima N, et al. Brain Res Mol Brain Res, 1993 Jul. PMID 8361332
  3. Nucleotide sequences of two embryonic drebrins, developmentally regulated brain proteins, and developmental change in their mRNAs. Kojima N, et al. Brain Res, 1988 Nov. PMID 3208110
  4. Localization of Drebrin: Light Microscopy Study. Shirao T, et al. Adv Exp Med Biol, 2017. PMID 28865017
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in neuron projection morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axon extension IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of dendritic spine morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in postsynaptic actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin filament polymerization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in actin filament IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendrite IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of polarized growth IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
drebrin
Names
developmentally regulated brain protein
drebrin A

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396858.1 → NP_001383787.1  drebrin isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    UniProtKB/Swiss-Prot
    P18302, Q91358, Q91359
    Related
    ENSGALP00010012127.1, ENSGALT00010021218.1
    Conserved Domains (2) summary
    cd11281
    Location:4 → 139
    ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)
    PHA03247
    Location:371 → 585
    PHA03247; large tegument protein UL36; Provisional

  2. NM_001396859.1 → NP_001383788.1  drebrin isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000256
    UniProtKB/Swiss-Prot
    P18302, Q91358, Q91359
    Conserved Domains (2) summary
    cd11281
    Location:4 → 139
    ADF_drebrin_like; ADF homology domain of drebrin and actin-binding protein 1 (abp1)
    PHA03247
    Location:325 → 539
    PHA03247; large tegument protein UL36; Provisional

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9757143..9769410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046900316.1 → XP_046756272.1  drebrin isoform X3

  2. XM_046900314.1 → XP_046756270.1  drebrin isoform X2

    UniProtKB/TrEMBL
    A0A8V0XZK5
    Related
    ENSGALP00010012133.1, ENSGALT00010021226.1

  3. XM_046900313.1 → XP_046756269.1  drebrin isoform X1

  4. XM_046900317.1 → XP_046756273.1  drebrin isoform X4

    Related
    ENSGALP00010012130.1, ENSGALT00010021222.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    9762921..9775200 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926885.1 → XP_046782841.1  drebrin isoform X3

  2. XM_046926884.1 → XP_046782840.1  drebrin isoform X2

  3. XM_046926883.1 → XP_046782839.1  drebrin isoform X1

  4. XM_046926886.1 → XP_046782842.1  drebrin isoform X4

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P18302.4 GenPept UniProtKB/Swiss-Prot:P18302

Gene LinkOut

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Molecular Biology Databases
Research Materials