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ANXA2 annexin A2 [ Gallus gallus (chicken) ]

Gene ID: 396297, updated on 10-Oct-2024

Summary

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Official Symbol
ANXA2provided by CGNC
Official Full Name
annexin A2provided by CGNC
Primary source
CGNC:49740
See related
Ensembl:ENSGALG00010024693
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
ANX2; ANXA2P2
Orthologs
human mouse all
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Genomic context

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See ANXA2 in Genome Data Viewer
Location:
chromosome: 10
Exon count:
18
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (5093832..5126129)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (4967961..5000301)

Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene RAR related orphan receptor A Neighboring gene uncharacterized LOC121111661 Neighboring gene uncharacterized LOC107052149 Neighboring gene uncharacterized LOC124417124 Neighboring gene uncharacterized LOC121111665 Neighboring gene interactor of little elongation complex ELL subunit 2 Neighboring gene uncharacterized LOC121113486 Neighboring gene forkhead box B1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of novel viral receptors with cell line expressing viral receptor-binding protein. Mei M, et al. Sci Rep, 2015 Jan 21. PMID 25604889, Free PMC Article
  2. Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Krishnan S, et al. Dev Biol, 2004 Jan 1. PMID 14697359
  3. The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. Kirsch T, et al. J Biol Chem, 2000 Nov 10. PMID 10956650
  4. p36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphiphatic helix. Johnsson N, et al. EMBO J, 1988 Aug. PMID 2973411, Free PMC Article
  5. The cDNA sequence of chicken annexin II. Gerke V, et al. Nucleic Acids Res, 1990 Jul 25. PMID 2143014, Free PMC Article

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. These results indicate, for the first time, that binding to Anx2 is beneficial for infectious bursal disease virus infection.
    Title: Binding chicken Anx2 is beneficial for infection with infectious bursal disease virus.
  2. chicken Annexin A2 (chANXA2) as a novel receptor for retrovirus ALV-J (avian leukosis virus subgroup J).
    Title: Identification of novel viral receptors with cell line expressing viral receptor-binding protein.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
annexin A2
Names
PAP-IV
annexin A2 pseudogene 2
annexin II
annexin-2
calpactin I heavy chain
calpactin-1 heavy chain
chromobindin-8
lipocortin II
p36
placental anticoagulant protein IV
protein I

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205351.2 → NP_990682.1  annexin A2

    See identical proteins and their annotated locations for NP_990682.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000245
    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18, A0A8V0ZZ99
    Related
    ENSGALP00010037051.1, ENSGALT00010060292.1
    Conserved Domains (1) summary
    pfam00191
    Location:109 → 174
    Annexin

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    5093832..5126129
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040706203.2 → XP_040562137.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18, A0A8V0ZZ99
    Conserved Domains (1) summary
    pfam00191
    Location:109 → 174
    Annexin

  2. XM_015278763.4 → XP_015134249.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18, A0A8V0ZZ99
    Conserved Domains (1) summary
    pfam00191
    Location:109 → 174
    Annexin

  3. XM_025153801.3 → XP_025009569.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18, A0A8V0ZZ99
    Related
    ENSGALP00010037063.1, ENSGALT00010060304.1
    Conserved Domains (1) summary
    pfam00191
    Location:109 → 174
    Annexin

  4. XM_025153803.3 → XP_025009571.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18, A0A8V0ZZ99
    Conserved Domains (1) summary
    pfam00191
    Location:109 → 174
    Annexin

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4967961..5000301
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046924548.1 → XP_046780504.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18

  2. XM_046924552.1 → XP_046780508.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18

  3. XM_046924549.1 → XP_046780505.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18

  4. XM_046924553.1 → XP_046780509.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18

  5. XM_046924550.1 → XP_046780506.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18

  6. XM_046924551.1 → XP_046780507.1  annexin A2 isoform X1

    UniProtKB/Swiss-Prot
    P17785
    UniProtKB/TrEMBL
    A0A1C9KD18
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P17785.2 GenPept UniProtKB/Swiss-Prot:P17785

Gene LinkOut

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