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GABRQ gamma-aminobutyric acid (GABA) A receptor, theta [ Gallus gallus (chicken) ]

Gene ID: 396288, updated on 17-Aug-2024

Summary

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Symbol
GABRQprovided by CGNC
Full Name
gamma-aminobutyric acid (GABA) A receptor, thetaprovided by CGNC
Primary source
CGNC:10584
See related
Ensembl:ENSGALG00010015078
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GABRB1; GABRB4
Orthologs
human mouse all
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Genomic context

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See GABRQ in Genome Data Viewer
Location:
chromosome: 4
Exon count:
9
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 4 NC_052535.1 (10602006..10668701, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 4 NC_052576.1 (10636094..10703038, complement)

Chromosome 4 - NC_052535.1Genomic Context describing neighboring genes Neighboring gene microRNA 1750 Neighboring gene uncharacterized LOC121110605 Neighboring gene uncharacterized LOC124417914 Neighboring gene uncharacterized LOC121110682 Neighboring gene gamma-aminobutyric acid type A receptor alpha3 subunit Neighboring gene gamma-aminobutyric acid type A receptor gamma3 subunit

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. gamma-Aminobutyric acidA receptor heterogeneity is increased by alternative splicing of a novel beta-subunit gene transcript. Bateson AN, et al. J Neurochem, 1991 Apr. PMID 1848280
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GABA-A receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables extracellular ligand-gated monoatomic ion channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables neurotransmitter receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GABA-A receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gamma-aminobutyric acid receptor subunit beta-4
Names
GABA(A) receptor subunit beta-4
GABA-A receptor, beta-4 subunit
gamma-aminobutyric acid (GABA) A receptor, beta 1
gamma-aminobutyric acid (GABA) receptor, theta
gamma-aminobutyric acid type A receptor theta subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001167703.2 → NP_001161175.1  gamma-aminobutyric acid receptor subunit beta-4 isoform 1 precursor

    See identical proteins and their annotated locations for NP_001161175.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAENSK010000071
    UniProtKB/Swiss-Prot
    P24045, Q6LBM6
    Conserved Domains (3) summary
    TIGR00860
    Location:15 → 486
    LIC; Cation transporter family protein
    pfam02931
    Location:37 → 242
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:249 → 483
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

  2. NM_001167704.2 → NP_001161176.1  gamma-aminobutyric acid receptor subunit beta-4 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    JAENSK010000071
    UniProtKB/Swiss-Prot
    P24045
    Related
    ENSGALP00010021098.1, ENSGALT00010036285.1
    Conserved Domains (3) summary
    TIGR00860
    Location:15 → 482
    LIC; Cation transporter family protein
    pfam02931
    Location:37 → 242
    Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
    pfam02932
    Location:249 → 479
    Neur_chan_memb; Neurotransmitter-gated ion-channel transmembrane region

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052535.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    10602006..10668701 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052576.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    10636094..10703038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P24045.1 GenPept UniProtKB/Swiss-Prot:P24045

Gene LinkOut

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