SST1 somatostatin 1 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: SST1provided by CGNC
Official Full Name: somatostatin 1provided by CGNC
Primary source: CGNC:5562
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: SS; SS1; SST; PSS1; SRIF; SS14
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 9

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	9	NC_052540.1 (14501234..14502767)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	9	NC_052581.1 (14297154..14298687)

Chromosome 9 - NC_052540.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mesendoderm-derived somatostatin promotes aPP identity in the overlying ectoderm by regulating Eya2 and nociceptin. Nociceptin controls its own expression and, together with somatostatin, the onset of Pax6, a key regulator of eye and olfactory fates.
Title: Neuropeptides: developmental signals in placode progenitor formation.
We conclude that much of the somatostatin-like immunoreactivity in the developing avian peripheral nervous system is actually cortistatin, the PSS2 product, as opposed to true somatostatin, which is the PSS1 product.
Title: The cortistatin gene PSS2 rather than the somatostatin gene PSS1 is strongly expressed in developing avian autonomic neurons.
SS14 and SS28 modulate cone photoreceptor cyclic GMP-gated channels through multiple mechanisms
Title: Somatostatin peptides produce multiple effects on gating properties of native cone photoreceptor cGMP-gated channels that depend on circadian phase and previous illumination.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables hormone activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of cell migration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: somatostatin

Names: somatostatin-14; somatostatin-28

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205336.1 → NP_990667.1 somatostatin precursor

See identical proteins and their annotated locations for NP_990667.1

Status: PROVISIONAL

Source sequence(s)

X60191

UniProtKB/Swiss-Prot

P33094

UniProtKB/TrEMBL

A5YW27, Q6Q7A1

Conserved Domains (1) summary

pfam03002
Location:99 → 116

Somatostatin; Somatostatin/Cortistatin family