CALB2 calbindin 2 [Gallus gallus (chicken)] - Gene

Summary

Official Symbol: CALB2provided by CGNC
Official Full Name: calbindin 2provided by CGNC
Primary source: CGNC:66223
See related: Ensembl:ENSGALG00010022382
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 11

Exon count:: 11

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	11	NC_052542.1 (1508754..1513331, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	11	NC_052583.1 (1681017..1685592, complement)

Chromosome 11 - NC_052542.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Calretinin does not play any significant role in the retina during postnatal development.
Title: Calbindin-D28k and calretinin in chicken inner retina during postnatal development and neuroplasticity by dim red light.
visinin and calretinin are induced by NeuroD in developing retinal cells
Title: NeuroD induces the expression of visinin and calretinin by proliferating cells derived from toxin-damaged chicken retina.
A novel division was identified (calbindin-rich, calretinin-rich), interposed between hyper- and mesopallium and related to the lamina separating both, termed laminar pallial nucleus. This gave rise at its surface to part of the lateral hyperpallium.
Title: Calcium-binding proteins, neuronal nitric oxide synthase, and GABA help to distinguish different pallial areas in the developing and adult chicken. I. Hippocampal formation and hyperpallium.

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables calcium ion binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of long-term synaptic potentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of presynaptic cytosolic calcium ion concentration	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed
located_in dendrite	IEA Inferred from Electronic Annotation more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info	PubMed
located_in synapse	IEA Inferred from Electronic Annotation more info	PubMed
located_in terminal bouton	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: calretinin

Names: CR

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205316.2 → NP_990647.1 calretinin

See identical proteins and their annotated locations for NP_990647.1

Status: VALIDATED

Source sequence(s)

JAENSK010000247

UniProtKB/Swiss-Prot

P07090

UniProtKB/TrEMBL

A0A8V0ZQD6

Related

ENSGALP00010032871.1, ENSGALT00010054419.1

Conserved Domains (1) summary

cd16177
Location:19 → 266

EFh_HEF_CR; EF-hand, calcium binding motif, found in calretinin (CR)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

1508754..1513331 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_040707011.2 → XP_040562945.1 calretinin isoform X1

UniProtKB/TrEMBL

A0A8V0ZQD6

Conserved Domains (2) summary

cd15902
Location:19 → 47

EFh_HEF; EF-hand motif [structural motif]

cl23634
Location:19 → 248

EFh_HEF; EF-hand, calcium binding motif, found in the hexa-EF hand proteins family