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ITGA8 integrin subunit alpha 8 [ Gallus gallus (chicken) ]

Gene ID: 396225, updated on 10-Oct-2024

Summary

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Symbol
ITGA8provided by CGNC
Full Name
integrin subunit alpha 8provided by CGNC
Primary source
CGNC:6640
See related
Ensembl:ENSGALG00010003222
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See ITGA8 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
30
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (20243435..20344303)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (20273236..20373171)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109643 Neighboring gene family with sequence similarity 188 member A Neighboring gene uncharacterized LOC121109784 Neighboring gene uncharacterized LOC101752025 Neighboring gene family with sequence similarity 171, member A1 Neighboring gene uncharacterized LOC121110077

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization of the integrin alpha 8 subunit: a new integrin beta 1-associated subunit, which is prominently expressed on axons and on cells in contact with basal laminae in chick embryos. Bossy B, et al. EMBO J, 1991 Sep. PMID 1714374, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integrin alpha-8
Names
integrin alpha 8 subunit
integrin, alpha 8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205288.3 → NP_990619.2  integrin alpha-8 precursor

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000036
    UniProtKB/Swiss-Prot
    P26009
    UniProtKB/TrEMBL
    A0A8V0XJR5
    Related
    ENSGALP00010004512.1, ENSGALT00010007577.1
    Conserved Domains (1) summary
    smart00191
    Location:365 → 419
    Int_alpha; Integrin alpha (beta-propellor repeats)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    20243435..20344303
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281310.4 → XP_015136796.2  integrin alpha-8 isoform X1

    UniProtKB/Swiss-Prot
    P26009
    UniProtKB/TrEMBL
    A0A8V0XJQ7
    Related
    ENSGALP00010004502.1, ENSGALT00010007560.1
    Conserved Domains (1) summary
    smart00191
    Location:365 → 419
    Int_alpha; Integrin alpha (beta-propellor repeats)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    20273236..20373171
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910454.1 → XP_046766410.1  integrin alpha-8 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P26009.1 GenPept UniProtKB/Swiss-Prot:P26009

Gene LinkOut

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Molecular Biology Databases
Research Materials