HHEX hematopoietically expressed homeobox [Gallus gallus (chicken)] - Gene

Summary

Symbol: HHEXprovided by CGNC
Full Name: hematopoietically expressed homeoboxprovided by CGNC
Primary source: CGNC:66222
See related: Ensembl:ENSGALG00010018471
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as: PROBOX
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	6	NC_052537.1 (21499690..21504006, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	6	NC_052578.1 (21390999..21395316, complement)

Chromosome 6 - NC_052537.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Hex plays an important role in the initiation of feather morphogenesis
Title: Expression of Hex during feather bud development.
Hex is upstream of Wnt7a and beta-catenin and regulates the Wnt signaling pathway in feather bud initiation
Title: Involvement of Hex in the initiation of feather morphogenesis.

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in cell differentiation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: hematopoietically-expressed homeobox protein HHEX

Names: homeobox protein HEX; homeobox protein PRH

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_205252.2 → NP_990583.2 hematopoietically-expressed homeobox protein HHEX

Status: PROVISIONAL

Source sequence(s)

JAENSK010000232

UniProtKB/Swiss-Prot

Q05502

UniProtKB/TrEMBL

A0A8V0Z7N3

Related

ENSGALP00010026606.1, ENSGALT00010044673.1

Conserved Domains (1) summary

smart00389
Location:150 → 200

HOX; Homeodomain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052537.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

21499690..21504006 complement

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GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052578.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

21390999..21395316 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)