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HOXA11 homeobox A11 [ Gallus gallus (chicken) ]

Gene ID: 395327, updated on 10-Oct-2024

Summary

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Symbol
HOXA11provided by CGNC
Full Name
homeobox A11provided by CGNC
Primary source
CGNC:49268
See related
Ensembl:ENSGALG00010001848
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
GHOX1I; ghox-1I; chox-1.9
Orthologs
human mouse all
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Genomic context

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See HOXA11 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (32565244..32577832, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (32617830..32630377, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene homeobox A9 Neighboring gene HOXA10 antisense RNA Neighboring gene microRNA 196b Neighboring gene homeobox A10 Neighboring gene uncharacterized LOC107052544 Neighboring gene homeobox A13 Neighboring gene translation initiation factor IF-2-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The pattern of expression of the chicken homolog of HOX1I in the developing limb suggests a possible role in the ectodermal inhibition of chondrogenesis. Rogina B, et al. Dev Dyn, 1992 Jan. PMID 1347239
  2. Hoxa-11 and Hoxa-13 are involved in repression of MyoD during limb muscle development. Yamamoto M, et al. Dev Growth Differ, 2003 Oct-Dec. PMID 14706073
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Hoxa-11 and Hoxa-13 are involved in the negative regulation of MyoD expression in limb muscle precursors
    Title: Hoxa-11 and Hoxa-13 are involved in repression of MyoD during limb muscle development.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anatomical structure development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
homeobox protein Hox-A11
Names
homeo box A11
homeobox protein Hox-1.9
homeodomain-containing protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204619.2 → NP_989950.1  homeobox protein Hox-A11

    See identical proteins and their annotated locations for NP_989950.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000037
    UniProtKB/Swiss-Prot
    P31258
    UniProtKB/TrEMBL
    L7NTA2
    Related
    ENSGALP00010002498.1, ENSGALT00010004201.1
    Conserved Domains (2) summary
    pfam00046
    Location:228 → 281
    Homeobox; Homeobox domain
    pfam12045
    Location:26 → 167
    DUF3528; Protein of unknown function (DUF3528)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    32565244..32577832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040675298.2 → XP_040531232.1  homeobox protein Hox-A11 isoform X2

    UniProtKB/TrEMBL
    L7NSZ2
    Conserved Domains (1) summary
    smart00389
    Location:182 → 238
    HOX; Homeodomain

  2. XM_040675293.2 → XP_040531227.1  homeobox protein Hox-A11 isoform X1

    UniProtKB/TrEMBL
    L7NSZ2
    Conserved Domains (1) summary
    smart00389
    Location:185 → 241
    HOX; Homeodomain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    32617830..32630377 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910295.1 → XP_046766251.1  homeobox protein Hox-A11 isoform X2

  2. XM_046910294.1 → XP_046766250.1  homeobox protein Hox-A11 isoform X1

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
P31258.1 GenPept UniProtKB/Swiss-Prot:P31258

Gene LinkOut

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Research Materials