U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

HOXA7 homeobox A7 [ Gallus gallus (chicken) ]

Gene ID: 395290, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Symbol
HOXA7provided by CGNC
Full Name
homeobox A7provided by CGNC
Primary source
CGNC:8400
See related
Ensembl:ENSGALG00010001826
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
HOXA-7
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See HOXA7 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (32537106..32541395, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (32589691..32593981, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene homeobox A3 Neighboring gene uncharacterized LOC121109556 Neighboring gene homeobox A5 Neighboring gene homeobox A6 Neighboring gene homeobox A9 Neighboring gene HOXA10 antisense RNA Neighboring gene microRNA 1732 Neighboring gene microRNA 196b

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL. Starkova J, et al. Pediatr Blood Cancer, 2010 Dec 1. PMID 20672366
  2. Additional enhancer copies, with intact cdx binding sites, anteriorize Hoxa-7/lacZ expression in mouse embryos: evidence in keeping with an instructional cdx gradient. Gaunt SJ, et al. Int J Dev Biol, 2004 Sep. PMID 15470633
  3. Gradients and forward spreading of vertebrate Hox gene expression detected by using a Hox/lacZ transgene. Gaunt SJ. Dev Dyn, 2001 May. PMID 11357191
  4. HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells. Chung N, et al. Mol Biol Rep, 2009 Feb. PMID 17972163
  5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Low expression of HOXA7 RNA is associated with hyperdiploid leukemia.
    Title: HOX gene expression in phenotypic and genotypic subgroups and low HOXA gene expression as an adverse prognostic factor in pediatric ALL.
  2. HOXA7, HOXB3, HOXA3, and HOXB13 expression levels changed during angiogenesis, sugessting these proteins might be involved in the angiogenesis of hMSCs.
    Title: HOX gene analysis of endothelial cell differentiation in human bone marrow-derived mesenchymal stem cells.
  3. during development, Hox expression boundaries become set along instructional cdx gradients, formed by cdx decay in cells moving away from the primitive streak region
    Title: Additional enhancer copies, with intact cdx binding sites, anteriorize Hoxa-7/lacZ expression in mouse embryos: evidence in keeping with an instructional cdx gradient.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in anterior/posterior pattern specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
homeobox protein Hox-A7
Names
homeo box A7
homeodomain transcription factor HoxA-7

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_204595.3 → NP_989926.1  homeobox protein Hox-A7

    See identical proteins and their annotated locations for NP_989926.1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000037
    UniProtKB/Swiss-Prot
    Q90VZ9
    Related
    ENSGALP00010002453.1, ENSGALT00010004156.1
    Conserved Domains (1) summary
    pfam00046
    Location:133 → 186
    Homeobox; Homeobox domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    32537106..32541395 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046917815.1 → XP_046773771.1  homeobox protein Hox-A7 isoform X3

  2. XM_046917806.1 → XP_046773762.1  homeobox protein Hox-A7 isoform X3

  3. XM_046917800.1 → XP_046773756.1  homeobox protein Hox-A7 isoform X2

  4. XM_046917799.1 → XP_046773755.1  homeobox protein Hox-A7 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    32589691..32593981 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910293.1 → XP_046766249.1  homeobox protein Hox-A7 isoform X3

  2. XM_046910292.1 → XP_046766248.1  homeobox protein Hox-A7 isoform X3

  3. XM_046910291.1 → XP_046766247.1  homeobox protein Hox-A7 isoform X2

  4. XM_046910290.1 → XP_046766246.1  homeobox protein Hox-A7 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q90VZ9.1 GenPept UniProtKB/Swiss-Prot:Q90VZ9

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials