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USP7 ubiquitin specific peptidase 7 [ Gallus gallus (chicken) ]

Gene ID: 395126, updated on 10-Oct-2024

Summary

Symbol
USP7provided by CGNC
Full Name
ubiquitin specific peptidase 7provided by CGNC
Primary source
CGNC:5523
See related
Ensembl:ENSGALG00010018419
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
UBP
Orthologs
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Genomic context

See USP7 in Genome Data Viewer
Location:
chromosome: 14
Exon count:
35
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 14 NC_052545.1 (9929780..9994482)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 14 NC_052586.1 (9926101..9990808)

Chromosome 14 - NC_052545.1Genomic Context describing neighboring genes Neighboring gene chromosome 16 open reading frame 72 Neighboring gene uncharacterized LOC121106773 Neighboring gene skin secretory protein xP2 Neighboring gene lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog Neighboring gene calcium regulated heat stable protein 1

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of protein stability IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
ubiquitin carboxyl-terminal hydrolase 7
Names
deubiquitinating enzyme 7
ubiquitin specific peptidase 7 (herpes virus-associated)
ubiquitin specific protease 7
ubiquitin thioesterase 7
ubiquitin-specific-processing protease 7
NP_001334941.1
NP_989802.2
XP_040503244.2
XP_046756508.1
XP_046756509.1
XP_046756510.1
XP_046783223.1
XP_046783224.1
XP_046783225.1
XP_046783226.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348012.2NP_001334941.1  ubiquitin carboxyl-terminal hydrolase 7 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' coding region and contains a distinct 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    JAENSK010000257
    UniProtKB/Swiss-Prot
    Q6U7I1
    Conserved Domains (2) summary
    pfam12436
    Location:620686
    USP7_ICP0_bdg; ICP0-binding domain of Ubiquitin-specific protease 7
    cl02553
    Location:56634
    Peptidase_C19; Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyse bonds involving the carboxyl group of the C-terminal Gly ...
  2. NM_204471.3NP_989802.2  ubiquitin carboxyl-terminal hydrolase 7 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    JAENSK010000257
    UniProtKB/TrEMBL
    A0A8V0ZDG4
    Related
    ENSGALP00010026574.1, ENSGALT00010044632.1
    Conserved Domains (1) summary
    COG5077
    Location:561100
    COG5077; Ubiquitin carboxyl-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052545.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    9929780..9994482
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046900554.1XP_046756510.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X3

  2. XM_046900552.1XP_046756508.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZDG9
    Related
    ENSGALP00010026579.1, ENSGALT00010044639.1
  3. XM_046900553.1XP_046756509.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X3

  4. XM_040647310.2XP_040503244.2  ubiquitin carboxyl-terminal hydrolase 7 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Z5X3
    Related
    ENSGALP00010026550.1, ENSGALT00010044600.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052586.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    9926101..9990808
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046927270.1XP_046783226.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X3

  2. XM_046927267.1XP_046783223.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZDG9
  3. XM_046927269.1XP_046783225.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X3

  4. XM_046927268.1XP_046783224.1  ubiquitin carboxyl-terminal hydrolase 7 isoform X3