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wdr3 WD repeat domain 3 [ Xenopus tropicalis (tropical clawed frog) ]

Gene ID: 394852, updated on 4-Nov-2024

Summary

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Official Symbol
wdr3provided by Xenbase
Official Full Name
WD repeat domain 3provided by Xenbase
Primary source
Xenbase:XB-GENE-975167
See related
Ensembl:ENSXETG00000009920 AllianceGenome:Xenbase:XB-GENE-975167
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus tropicalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary
Predicted to enable snoRNA binding activity. Predicted to be involved in maturation of SSU-rRNA. Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleolus. Predicted to be part of Pwp2p-containing subcomplex of 90S preribosome and small-subunit processome. Human ortholog(s) of this gene implicated in papillary thyroid carcinoma. Orthologous to human WDR3 (WD repeat domain 3). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
human mouse all
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Genomic context

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See wdr3 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
29
Annotation release Status Assembly Chr Location
104 current UCB_Xtro_10.0 (GCF_000004195.4) 2 NC_030678.2 (2883380..2896355)
103 previous assembly Xenopus_tropicalis_v9.1 (GCF_000004195.3) Unplaced Scaffold NW_016683421.1 (382232..394033, complement)

Chromosome 2 - NC_030678.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105945835 Neighboring gene terminal nucleotidyltransferase 5C Neighboring gene ganglioside induced differentiation associated protein 2 Neighboring gene NADH:ubiquinone oxidoreductase subunit B4 Neighboring gene homogentisate 1,2-dioxygenase Neighboring gene RAB, member of RAS oncogene family-like 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC76073

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables snoRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
acts_upstream_of_or_within ribosome biogenesis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of Pwp2p-containing subcomplex of 90S preribosome IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in nucleolus IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  
part_of small-subunit processome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
WD repeat-containing protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_203911.1 → NP_989242.1  WD repeat-containing protein 3

    See identical proteins and their annotated locations for NP_989242.1

    Status: PROVISIONAL

    Source sequence(s)
    BC063906
    UniProtKB/TrEMBL
    A0A6I8QR95, A0A6I8RK87, A0A6I8SMF8, F6YLZ1, Q6P3Q1
    Related
    ENSXETP00000021860.4, ENSXETT00000021860.5
    Conserved Domains (4) summary
    cd00200
    Location:403 → 701
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:455 → 490
    7WD40; WD40 repeat [structural motif]
    pfam04003
    Location:802 → 905
    Utp12; Dip2/Utp12 Family
    cl29593
    Location:36 → 221
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Xenopus tropicalis Annotation Release 104 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference UCB_Xtro_10.0 Primary Assembly

Genomic

  1. NC_030678.2 Reference UCB_Xtro_10.0 Primary Assembly

    Range
    2883380..2896355
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031895809.1 → XP_031751669.1  WD repeat-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6I8QR95, A0A6I8RK87, A0A6I8SMF8, F6YLZ1, Q6P3Q1
    Conserved Domains (4) summary
    cd00200
    Location:403 → 701
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:455 → 490
    7WD40; WD40 repeat [structural motif]
    pfam04003
    Location:802 → 905
    Utp12; Dip2/Utp12 Family
    cl29593
    Location:36 → 221
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

  2. XM_031895810.1 → XP_031751670.1  WD repeat-containing protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A6I8QR95, A0A6I8RK87, A0A6I8SMF8, F6YLZ1, Q6P3Q1
    Related
    ENSXETP00000082670.2, ENSXETT00000081742.2
    Conserved Domains (4) summary
    cd00200
    Location:403 → 701
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    sd00039
    Location:455 → 490
    7WD40; WD40 repeat [structural motif]
    pfam04003
    Location:802 → 905
    Utp12; Dip2/Utp12 Family
    cl29593
    Location:36 → 221
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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