gpd1l glycerol-3-phosphate dehydrogenase 1 like [Xenopus tropicalis (tropical clawed frog)] - Gene

Summary

Official Symbol: gpd1lprovided by Xenbase
Official Full Name: glycerol-3-phosphate dehydrogenase 1 likeprovided by Xenbase
Primary source: Xenbase:XB-GENE-969902
See related: Ensembl:ENSXETG00000015022 AllianceGenome:Xenbase:XB-GENE-969902
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus tropicalis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana
Summary: Predicted to enable NAD binding activity; glycerol-3-phosphate dehydrogenase (NAD+) activity; and protein homodimerization activity. Predicted to act upstream of or within NADH oxidation; carbohydrate metabolic process; and glycerol-3-phosphate catabolic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Human ortholog(s) of this gene implicated in Brugada syndrome 2. Orthologous to human GPD1L (glycerol-3-phosphate dehydrogenase 1 like). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 6

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
104	current	UCB_Xtro_10.0 (GCF_000004195.4)	6	NC_030682.2 (50019478..50036574)
103	previous assembly	Xenopus_tropicalis_v9.1 (GCF_000004195.3)	6	NC_030682.1 (74130594..74147691, complement)

Chromosome 6 - NC_030682.2 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables NAD binding	IEA Inferred from Electronic Annotation more info
enables glycerol-3-phosphate dehydrogenase (NAD+) activity	IEA Inferred from Electronic Annotation more info
NOT enables glycerol-3-phosphate dehydrogenase [NAD(P)+] activity	IBA Inferred from Biological aspect of Ancestor more info
enables oxidoreductase activity	IEA Inferred from Electronic Annotation more info
enables oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	IEA Inferred from Electronic Annotation more info
enables protein homodimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
NOT involved_in NADH oxidation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within NADH oxidation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within carbohydrate metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within glycerol-3-phosphate catabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: glycerol-3-phosphate dehydrogenase 1-like protein

NP_989027.1

EC 1.1.1.8

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_203696.1 → NP_989027.1 glycerol-3-phosphate dehydrogenase 1-like protein

See identical proteins and their annotated locations for NP_989027.1

Status: PROVISIONAL

Source sequence(s)

BC061407

UniProtKB/Swiss-Prot

Q6P824

UniProtKB/TrEMBL

A0A803JII3

Related

ENSXETP00000113270.1, ENSXETT00000123565.1

Conserved Domains (1) summary

TIGR03376
Location:8 → 345

glycerol3P_DH; glycerol-3-phosphate dehydrogenase (NAD(+))