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abi2.S abl-interactor 2 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 394360, updated on 4-Nov-2024

Summary

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Official Symbol
abi2.S
Official Full Name
abl-interactor 2 S homeolog
Primary source
Xenbase:XB-GENE-944595
Locus tag
XELAEV_18047340mg
See related
EnsemblRapid:ENSXLAG00005033815 AllianceGenome:Xenbase:XB-GENE-944595
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
abi2; Xlan4; abi-2; abi2.L; lan4-a
Summary
Predicted to enable SH3 domain binding activity and signaling adaptor activity. Predicted to act upstream of or within neuron migration. Predicted to be located in filopodium and lamellipodium. Predicted to be part of SCAR complex. Orthologous to human ABI2 (abl interactor 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See abi2.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (77423422..77459130, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (70789931..70825836, complement)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene CD28 molecule S homeolog Neighboring gene Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 S homeolog Neighboring gene cytochrome P450 family 20 subfamily A member 1 S homeolog Neighboring gene aldehyde oxidase 1 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The cloning and characterization of a localized maternal transcript in Xenopus laevis whose zygotic counterpart is detected in the CNS. Reddy BA, et al. Mech Dev, 1992 Dec. PMID 1284029
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC79979

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables SH3 domain binding IEA
Inferred from Electronic Annotation
more info
  
enables signaling adaptor activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within neuron migration IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of SCAR complex IEA
Inferred from Electronic Annotation
more info
  
located_in actin-based cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in cell projection IEA
Inferred from Electronic Annotation
more info
  
located_in filopodium IEA
Inferred from Electronic Annotation
more info
  
located_in lamellipodium IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
abl-interactor 2 S homeolog
Names
abl-interactor 2 L homeolog
animal 4

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001087591.1 → NP_001081060.1  abl-interactor 2 S homeolog

    See identical proteins and their annotated locations for NP_001081060.1

    Status: PROVISIONAL

    Source sequence(s)
    M94969
    UniProtKB/TrEMBL
    Q03292
    Conserved Domains (1) summary
    cd11972
    Location:254 → 314
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    77423422..77459130 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041577666.1 → XP_041433600.1  abl-interactor 2 S homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1LXX0
    Conserved Domains (2) summary
    cd11972
    Location:428 → 488
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:220 → 427
    PHA03247; large tegument protein UL36; Provisional

  2. XM_041577668.1 → XP_041433602.1  abl-interactor 2 S homeolog isoform X7

    UniProtKB/TrEMBL
    A0A8J1LVP2
    Conserved Domains (2) summary
    cd11972
    Location:422 → 482
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:214 → 421
    PHA03247; large tegument protein UL36; Provisional

  3. XM_041577665.1 → XP_041433599.1  abl-interactor 2 S homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1LW50
    Related
    ENSXLAP00005100984.1, ENSXLAT00005102954.1
    Conserved Domains (2) summary
    cd11972
    Location:429 → 489
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:221 → 423
    PHA03247; large tegument protein UL36; Provisional

  4. XM_041577664.1 → XP_041433598.1  abl-interactor 2 S homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1LVR2, A0A974BUX4
    Conserved Domains (2) summary
    cd11972
    Location:478 → 538
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:193 → 477
    PHA03247; large tegument protein UL36; Provisional

  5. XM_041577663.1 → XP_041433597.1  abl-interactor 2 S homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1LVN8, A0A974BUX4
    Related
    ENSXLAP00005101117.1, ENSXLAT00005103091.1
    Conserved Domains (2) summary
    cd11972
    Location:479 → 539
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:187 → 415
    PHA03247; large tegument protein UL36; Provisional

  6. XM_041577667.1 → XP_041433601.1  abl-interactor 2 S homeolog isoform X6

    UniProtKB/TrEMBL
    A0A8J1LX21
    Conserved Domains (2) summary
    cd11972
    Location:423 → 483
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
    PHA03247
    Location:215 → 417
    PHA03247; large tegument protein UL36; Provisional

  7. XM_018237281.2 → XP_018092770.1  abl-interactor 2 S homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J0TQ63, A0A974BUX4
    Related
    ENSXLAP00005101224.1, ENSXLAT00005103199.1

  8. XM_041577670.1 → XP_041433604.1  abl-interactor 2 S homeolog isoform X9

    UniProtKB/TrEMBL
    A0A8J1LW57, A0A974BUX4
    Conserved Domains (1) summary
    cd11972
    Location:418 → 478
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2

  9. XM_041577673.1 → XP_041433607.1  abl-interactor 2 S homeolog isoform X13

    UniProtKB/TrEMBL
    A0A8J1LVP7, A0A974BUX4
    Conserved Domains (1) summary
    cd11972
    Location:362 → 422
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2

  10. XM_018237284.2 → XP_018092773.1  abl-interactor 2 S homeolog isoform X10

    UniProtKB/TrEMBL
    A0A8J0TXJ3, A0A974BUX4
    Related
    ENSXLAP00005101189.1, ENSXLAT00005103163.1

  11. XM_041577671.1 → XP_041433605.1  abl-interactor 2 S homeolog isoform X11

    UniProtKB/TrEMBL
    A0A8J1LXX7, A0A974BUX4
    Conserved Domains (1) summary
    cd11972
    Location:369 → 429
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2

  12. XM_041577669.1 → XP_041433603.1  abl-interactor 2 S homeolog isoform X8

    UniProtKB/TrEMBL
    A0A8J1LVR7, A0A974BUX4
    Related
    ENSXLAP00005101070.1, ENSXLAT00005103045.1
    Conserved Domains (1) summary
    cd11972
    Location:419 → 479
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2

  13. XM_041577672.1 → XP_041433606.1  abl-interactor 2 S homeolog isoform X12

    UniProtKB/TrEMBL
    A0A8J1LX26, A0A974BUX4
    Conserved Domains (1) summary
    cd11972
    Location:363 → 423
    SH3_Abi2; Src homology 3 domain of Abl Interactor 2
Nucleotide Protein Strain
Heading Accession and Version

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